Liposomal lidocaine — Competitive Intelligence Brief

Liposomal lidocaine (Liposomal lidocaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia/Pain Management.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia/Pain Management Small molecule

Target snapshot

Liposomal lidocaine (Liposomal lidocaine) — The Hospital for Sick Children. Liposomal lidocaine is a local anesthetic encapsulated in liposomes that blocks sodium channels in nerve cell membranes to prevent pain signal transmission.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Liposomal lidocaine TARGET	Liposomal lidocaine	The Hospital for Sick Children	marketed	Local anesthetic	Voltage-gated sodium channels
Transdermal Lidocaine Patch	Transdermal Lidocaine Patch	University of Wisconsin, Madison	marketed	Local anesthetic	Voltage-gated sodium channels
SUP Lidocaine	SUP Lidocaine	University of Michigan	marketed	Local anesthetic	Voltage-gated sodium channels
Topiramate monotherapy	Topiramate monotherapy	Johnson & Johnson Taiwan Ltd	marketed	Anticonvulsant / Antiepileptic agent	GABA-A receptor; voltage-gated sodium channels
Anesthetic Topical Adhesive Synera	Anesthetic Topical Adhesive Synera	Brown, Theodore R., M.D., MPH	marketed	Topical local anesthetic	Voltage-gated sodium channels
Levobupivacaine 0.5% + epinephrin 1/200000	Levobupivacaine 0.5% + epinephrin 1/200000	University Hospital, Antwerp	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-adrenergic receptors
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class