Ketoprofen topical — Competitive Intelligence Brief

Ketoprofen topical (Ketoprofen topical) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NSAID (nonsteroidal anti-inflammatory drug). Area: Pain Management, Rheumatology.

phase 3 NSAID (nonsteroidal anti-inflammatory drug) COX-1, COX-2 Pain Management, Rheumatology Small molecule

Target snapshot

Ketoprofen topical (Ketoprofen topical) — Handok Inc.. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain at the site of topical application.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ketoprofen topical TARGET	Ketoprofen topical	Handok Inc.	phase 3	NSAID (nonsteroidal anti-inflammatory drug)	COX-1, COX-2
Diclofenac diethylamine 1.16% gel	Diclofenac diethylamine 1.16% gel	Novartis	marketed	NSAID (nonsteroidal anti-inflammatory drug)	COX-1, COX-2
Acular LS	Acular LS	University of Colorado, Denver	marketed	Topical NSAID	COX-1, COX-2
Non- effervescent Paracetamol kern	Non- effervescent Paracetamol kern	Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina	marketed	Analgesic and antipyretic	Cyclooxygenase (COX-1, COX-2)
Aspirin, Acetaminophen, Caffeine pills	Aspirin, Acetaminophen, Caffeine pills	Albert Einstein Healthcare Network	marketed	Analgesic combination product	Cyclooxygenase (COX-1, COX-2); adenosine receptors (caffeine)
Pranoprofen Eyedrops	Pranoprofen Eyedrops	Università degli Studi di Brescia	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	Cyclooxygenase (COX-1, COX-2)
Naproxen Sodium + Codeine Phosphate	Naproxen Sodium + Codeine Phosphate	ibrahim doğru	marketed	NSAID + opioid analgesic combination	COX-1, COX-2, mu-opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NSAID (nonsteroidal anti-inflammatory drug) class)

1. Depomed · 1 drug in this class
2. Dong-A ST Co., Ltd. · 1 drug in this class
3. Handok Inc. · 1 drug in this class
4. Imprimis Pharmaceuticals, Inc. · 1 drug in this class
5. Kunming Baker Norton Pharmaceutical Sales Co., Ltd. · 1 drug in this class
6. LEO Pharma · 1 drug in this class
7. Novartis · 1 drug in this class
8. Pfizer · 1 drug in this class
9. University of South Alabama · 1 drug in this class
10. ZARS Pharma Inc. · 1 drug in this class