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Pranoprofen Eyedrops
Pranoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes to reduce prostaglandin synthesis and inflammation in the eye.
Pranoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes to reduce prostaglandin synthesis and inflammation in the eye. Used for Postoperative inflammation and pain following ocular surgery, Allergic conjunctivitis, Seasonal allergic rhinoconjunctivitis.
At a glance
| Generic name | Pranoprofen Eyedrops |
|---|---|
| Sponsor | Università degli Studi di Brescia |
| Drug class | Nonsteroidal anti-inflammatory drug (NSAID) |
| Target | Cyclooxygenase (COX-1, COX-2) |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
As an NSAID formulated as an ophthalmic solution, pranoprofen works by blocking COX-1 and COX-2 enzymes, thereby decreasing prostaglandin production in ocular tissues. This reduces inflammation, pain, and photophobia associated with various ocular conditions. The drug is applied topically to the eye where it exerts local anti-inflammatory effects.
Approved indications
- Postoperative inflammation and pain following ocular surgery
- Allergic conjunctivitis
- Seasonal allergic rhinoconjunctivitis
Common side effects
- Ocular irritation or stinging
- Conjunctival hyperemia
- Transient corneal erosion
- Photophobia
Key clinical trials
- Iris Vascular Area Density-Based Preoperative Pain-Risk Screening and Intervention in Second-Eye Cataract Surgery (PHASE4)
- Analysis of Postoperative Ocular Surface Changes and Intervention Effect After PPV in MGD Dry Eye Patients (PHASE4)
- Nutraceutical Support With Omega-3 (NA)
- Treatment of CNV With Aflibercept Combined With Pranoprofen Eye Drops or Nutraceutical Support With Omega-3 (PHASE4)
- Observation on the Herpes Simplex Keratitis
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Pranoprofen Eyedrops CI brief — competitive landscape report
- Pranoprofen Eyedrops updates RSS · CI watch RSS
- Università degli Studi di Brescia portfolio CI