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ketoprofen and cyclobenzaprine association — Competitive Intelligence Brief

ketoprofen and cyclobenzaprine association (ketoprofen and cyclobenzaprine association) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NSAID and muscle relaxant. Area: Pain management.

phase 3 NSAID and muscle relaxant COX-1 and COX-2 Pain management Small molecule Live · refreshed every 30 min

Target snapshot

ketoprofen and cyclobenzaprine association (ketoprofen and cyclobenzaprine association) — EMS. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and inflammation, while cyclobenzaprine is a muscle relaxant that acts as a central nervous system depressant, affecting the brain's motor control centers.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ketoprofen and cyclobenzaprine association TARGET ketoprofen and cyclobenzaprine association EMS phase 3 NSAID and muscle relaxant COX-1 and COX-2
Cytotec Misoprostol Pfizer marketed NSAID combined with prostaglandin analog Cyclooxygenase (COX-1 and COX-2); Prostaglandin receptors 1988-01-01
Codeine + Diclofenac Codeine + Diclofenac University of Sao Paulo marketed Opioid + NSAID combination analgesic Mu opioid receptor (codeine); COX-1 and COX-2 (diclofenac)
Nepafenac (Nevanac) Nepafenac (Nevanac) Center For Excellence In Eye Care marketed Nonsteroidal anti-inflammatory drug (NSAID) Cyclooxygenase (COX-1 and COX-2)
NSAID (Ketorolac/Ibuprofen) NSAID (Ketorolac/Ibuprofen) Thomas Jefferson University marketed Non-steroidal anti-inflammatory drug (NSAID) COX-1 and COX-2
morphine ,ketorolac morphine ,ketorolac Jose Antonio Bernia Gil marketed Opioid analgesic + NSAID combination Opioid receptors (μ, δ, κ); COX-1 and COX-2 enzymes
Diclofenac 1% Diclofenac 1% Daré Bioscience, Inc. marketed Nonsteroidal anti-inflammatory drug (NSAID) COX-1 and COX-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NSAID and muscle relaxant class)

  1. EMS · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ketoprofen and cyclobenzaprine association — Competitive Intelligence Brief. https://druglandscape.com/ci/ketoprofen-and-cyclobenzaprine-association. Accessed 2026-05-17.

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