Who are Ivacaftor Exposed's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Symdeko (Copackaged), Ivacaftor+lumacaftor, TEZ, Ivacaftor (VX-770), IVA, Ivacaftor and Symdeko.

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Last reviewed 2026-06-10 · How we verify

Ivacaftor Exposed — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ivacaftor Exposed (Ivacaftor Exposed) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CFTR potentiator. Area: Respiratory.

phase 2 CFTR potentiator CFTR Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Ivacaftor Exposed (Ivacaftor Exposed) — Vertex Pharmaceuticals Incorporated. Potentiates CFTR chloride channel function

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ivacaftor Exposed TARGET	Ivacaftor Exposed	Vertex Pharmaceuticals Incorporated	phase 2	CFTR potentiator	CFTR
Symdeko (Copackaged)	TEZACAFTOR	Vertex Pharms	marketed		CFTR	2018-01-01
Ivacaftor+lumacaftor	Ivacaftor+lumacaftor	Assistance Publique - Hôpitaux de Paris	marketed	CFTR modulator combination (corrector + potentiator)	CFTR (cystic fibrosis transmembrane conductance regulator)
TEZ	TEZ	Vertex Pharmaceuticals Incorporated	marketed	CFTR corrector	CFTR (cystic fibrosis transmembrane conductance regulator)
Ivacaftor (VX-770)	Ivacaftor (VX-770)	University of Alabama at Birmingham	marketed	CFTR potentiator	CFTR (cystic fibrosis transmembrane conductance regulator)
IVA	IVA	Vertex Pharmaceuticals Incorporated	marketed	CFTR potentiator	CFTR (cystic fibrosis transmembrane conductance regulator)
Ivacaftor and Symdeko	Ivacaftor and Symdeko	University of Alabama at Birmingham	marketed	CFTR modulator (potentiator and corrector combination)	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-07-06 — Symdeko (Copackaged) · 8354427 · US
2026-12-28 — Symdeko (Copackaged) · 9931334 · US
2026-12-28 — Symdeko (Copackaged) · 9670163 · US
2026-12-28 — Symdeko (Copackaged) · 8754224 · US
2026-12-28 — Symdeko (Copackaged) · 8410274 · US
2027-04-09 — Symdeko (Copackaged) · 10239867 · US
2027-04-09 — Symdeko (Copackaged) · 9974781 · US
2027-04-09 — Symdeko (Copackaged) · 11639347 · US
2027-04-09 — Symdeko (Copackaged) · 10022352 · US
2027-05-01 — Symdeko (Copackaged) · 8598181 · US
2027-05-01 — Symdeko (Copackaged) · 7645789 · US
2027-05-01 — Symdeko (Copackaged) · 8623905 · US
2027-05-20 — Symdeko (Copackaged) · 7495103 · US
2027-06-03 — Symdeko (Copackaged) · 7776905 · US
2027-08-05 — Symdeko (Copackaged) · 8324242 · US
2027-11-12 — Symdeko (Copackaged) · 8415387 · US
2029-08-13 — Symdeko (Copackaged) · 11564916 · US
2029-08-13 — Symdeko (Copackaged) · 10646481 · US
2031-03-25 — Symdeko (Copackaged) · 10081621 · US
2031-03-25 — Symdeko (Copackaged) · 11578062 · US
2033-07-15 — Symdeko (Copackaged) · 10058546 · US
2033-07-15 — Symdeko (Copackaged) · 9012496 · US
2035-04-14 — Symdeko (Copackaged) · 10206877 · US

Sponsor landscape (CFTR potentiator class)

Vertex Pharmaceuticals Incorporated · 4 drugs in this class
Jennifer Taylor-Cousar · 1 drug in this class
University of Alabama at Birmingham · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ivacaftor Exposed — Competitive Intelligence Brief. https://druglandscape.com/ci/ivacaftor-exposed. Accessed 2026-06-10.

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