Who are IV isotonic bicarbonate's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Intravenous sodium bicarbonate, trisodium citrate, Experimental - 4% Sodium Bicarbonate, Sodium Bicarbonate 7.5% Injection, sodium bicarbonate 8.4%, Intensive treatment with sodium bicarbonate.

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Last reviewed 2026-05-16 · How we verify

IV isotonic bicarbonate — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

IV isotonic bicarbonate (IV isotonic bicarbonate) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkalinizing agent. Area: Critical Care / Metabolic Disorders.

phase 3 Alkalinizing agent Critical Care / Metabolic Disorders Small molecule Live · refreshed every 30 min

Target snapshot

IV isotonic bicarbonate (IV isotonic bicarbonate) — VA Office of Research and Development. IV isotonic bicarbonate restores acid-base balance by increasing serum bicarbonate concentration to counteract metabolic acidosis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
IV isotonic bicarbonate TARGET	IV isotonic bicarbonate	VA Office of Research and Development	phase 3	Alkalinizing agent
Intravenous sodium bicarbonate	Intravenous sodium bicarbonate	The Western Pennsylvania Hospital	marketed	Alkalinizing agent
trisodium citrate	trisodium citrate	Onze Lieve Vrouwe Gasthuis	marketed	Anticoagulant / Alkalinizing agent	Ionized calcium (Ca2+)
Experimental - 4% Sodium Bicarbonate	Experimental - 4% Sodium Bicarbonate	Baptist Health South Florida	marketed	Antacid / Alkalinizing agent
Sodium Bicarbonate 7.5% Injection	Sodium Bicarbonate 7.5% Injection	Hospital General "Dr. Miguel Silva" de Morelia	marketed	Alkalinizing agent
sodium bicarbonate 8.4%	sodium bicarbonate 8.4%	University of Baghdad	marketed	Alkalinizing agent
Intensive treatment with sodium bicarbonate	Intensive treatment with sodium bicarbonate	University of Roma La Sapienza	marketed	pH modulator / alkalinizing agent

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Alkalinizing agent class)

Hospital General "Dr. Miguel Silva" de Morelia · 1 drug in this class
Jennifer Gassman, PhD · 1 drug in this class
The Western Pennsylvania Hospital · 1 drug in this class
University of Baghdad · 1 drug in this class
VA Greater Los Angeles Healthcare System · 1 drug in this class
VA Office of Research and Development · 1 drug in this class

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Cite this brief

Drug Landscape (2026). IV isotonic bicarbonate — Competitive Intelligence Brief. https://druglandscape.com/ci/iv-isotonic-bicarbonate. Accessed 2026-05-16.

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