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isoniazid , randomized, open label — Competitive Intelligence Brief
phase 3
Antitubercular agent
InhA
Infectious disease
Small molecule
Live · refreshed every 30 min
Target snapshot
isoniazid , randomized, open label (isoniazid , randomized, open label) — National Taiwan University Hospital. Isoniazid inhibits the synthesis of mycolic acid in Mycobacterium tuberculosis by inhibiting the enzyme enoyl-acyl carrier protein reductase (InhA).
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| isoniazid , randomized, open label TARGET | isoniazid , randomized, open label | National Taiwan University Hospital | phase 3 | Antitubercular agent | InhA | |
| Preventive treatment with Isoniazid | Preventive treatment with Isoniazid | Hospital Universitari de Bellvitge | marketed | Antimycobacterial agent | InhA (enoyl-ACP reductase); KatG (catalase-peroxidase) | |
| Isoniazid (Rifinah) | Isoniazid (Rifinah) | National Taiwan University Hospital | marketed | Antituberculous agent | Enoyl-ACP reductase (InhA) | |
| Isoniazid (INH) | Isoniazid (INH) | National Institutes of Health Clinical Center (CC) | marketed | Antituberculous agent | InhA (enoyl-ACP reductase) | |
| INH preventive therapy | INH preventive therapy | Johns Hopkins University | marketed | Antimycobacterial agent | InhA (enoyl-ACP reductase) | |
| Isoniazid (H) | Isoniazid (H) | University College, London | phase 3 | Nicotinamide analog; first-line antituberculous agent | Enoyl-ACP reductase (InhA); catalase-peroxidase (KatG) | |
| Isoniazid with Ethambutol | Isoniazid with Ethambutol | Tuberculosis Research Centre, India | phase 3 | Antituberculous agents | InhA (isoniazid); arabinosyl transferases (ethambutol) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antitubercular agent class)
- National Taiwan University Hospital · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). isoniazid , randomized, open label — Competitive Intelligence Brief. https://druglandscape.com/ci/isoniazid-randomized-open-label. Accessed 2026-05-14.
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