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isoniazid , randomized, open label — Competitive Intelligence Brief

isoniazid , randomized, open label (isoniazid , randomized, open label) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antitubercular agent. Area: Infectious disease.

phase 3 Antitubercular agent InhA Infectious disease Small molecule Live · refreshed every 30 min

Target snapshot

isoniazid , randomized, open label (isoniazid , randomized, open label) — National Taiwan University Hospital. Isoniazid inhibits the synthesis of mycolic acid in Mycobacterium tuberculosis by inhibiting the enzyme enoyl-acyl carrier protein reductase (InhA).

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
isoniazid , randomized, open label TARGET isoniazid , randomized, open label National Taiwan University Hospital phase 3 Antitubercular agent InhA
Preventive treatment with Isoniazid Preventive treatment with Isoniazid Hospital Universitari de Bellvitge marketed Antimycobacterial agent InhA (enoyl-ACP reductase); KatG (catalase-peroxidase)
Isoniazid (Rifinah) Isoniazid (Rifinah) National Taiwan University Hospital marketed Antituberculous agent Enoyl-ACP reductase (InhA)
Isoniazid (INH) Isoniazid (INH) National Institutes of Health Clinical Center (CC) marketed Antituberculous agent InhA (enoyl-ACP reductase)
INH preventive therapy INH preventive therapy Johns Hopkins University marketed Antimycobacterial agent InhA (enoyl-ACP reductase)
Isoniazid (H) Isoniazid (H) University College, London phase 3 Nicotinamide analog; first-line antituberculous agent Enoyl-ACP reductase (InhA); catalase-peroxidase (KatG)
Isoniazid with Ethambutol Isoniazid with Ethambutol Tuberculosis Research Centre, India phase 3 Antituberculous agents InhA (isoniazid); arabinosyl transferases (ethambutol)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antitubercular agent class)

  1. National Taiwan University Hospital · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). isoniazid , randomized, open label — Competitive Intelligence Brief. https://druglandscape.com/ci/isoniazid-randomized-open-label. Accessed 2026-05-14.

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