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intra-rectal botulinum toxin injections — Competitive Intelligence Brief
phase 3
Neuromuscular blocker
SNARE proteins
Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
intra-rectal botulinum toxin injections (intra-rectal botulinum toxin injections) — University Hospital, Rouen. Botulinum toxin injections work by blocking the release of acetylcholine at the neuromuscular junction, leading to muscle relaxation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| intra-rectal botulinum toxin injections TARGET | intra-rectal botulinum toxin injections | University Hospital, Rouen | phase 3 | Neuromuscular blocker | SNARE proteins | |
| Botulinum toxin A 150u | Botulinum toxin A 150u | EvergreenHealth | marketed | Neurotoxin; Acetylcholine release inhibitor | SNARE proteins (specifically SNAP-25) | |
| botulinum type a | botulinum type a | Henry Ford Health System | marketed | Neurotoxin; botulinum toxin | SNARE proteins (synaptobrevin, SNAP-25, syntaxin); acetylcholine release machinery | |
| Botulinum Toxin A (Botox ) | Botulinum Toxin A (Botox ) | Assistance Publique - Hôpitaux de Paris | marketed | Neurotoxin; acetylcholine release inhibitor | SNARE proteins (specifically SNAP-25); acetylcholine release machinery | |
| Botulinum neurotoxin (BTX) | Botulinum neurotoxin (BTX) | The University of Texas Health Science Center, Houston | marketed | Neurotoxin; acetylcholine release inhibitor | SNARE proteins (SNAP-25, VAMP, syntaxin) | |
| Botulinum Toxin Type A Injection [HG102] | Botulinum Toxin Type A Injection [HG102] | Hugel | phase 3 | Neurotoxin; botulinum toxin preparation | SNARE proteins (synaptobrevin/VAMP); acetylcholine release machinery | |
| BOTOX®, Allergan | BOTOX®, Allergan | Assistance Publique - Hôpitaux de Paris | phase 3 | Botulinum toxin type A | SNARE proteins (specifically SNAP-25) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neuromuscular blocker class)
- Guy's and St Thomas' NHS Foundation Trust · 1 drug in this class
- University Hospital, Rouen · 1 drug in this class
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Cite this brief
Drug Landscape (2026). intra-rectal botulinum toxin injections — Competitive Intelligence Brief. https://druglandscape.com/ci/intra-rectal-botulinum-toxin-injections. Accessed 2026-05-16.
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