Who are Intra-arterial infusion of Alteplase's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Fibrinolytic twice daily, Fibrinolytic once daily, low-dose tenecteplase intravenous thrombolysis, Intravenous Tenecteplase, rhPro-UK simulation agent, Intravenous rhTNK-tPA.

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Last reviewed 2026-05-17 · How we verify

Intra-arterial infusion of Alteplase — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intra-arterial infusion of Alteplase (Intra-arterial infusion of Alteplase) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Fibrinolytic agent / Tissue plasminogen activator (tPA). Area: Cardiovascular.

phase 3 Fibrinolytic agent / Tissue plasminogen activator (tPA) Plasminogen / Fibrin Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Intra-arterial infusion of Alteplase (Intra-arterial infusion of Alteplase) — Central Hospital, Nancy, France. Alteplase is a tissue plasminogen activator (tPA) that converts plasminogen to plasmin, directly dissolving fibrin clots when delivered intra-arterially.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Intra-arterial infusion of Alteplase TARGET	Intra-arterial infusion of Alteplase	Central Hospital, Nancy, France	phase 3	Fibrinolytic agent / Tissue plasminogen activator (tPA)	Plasminogen / Fibrin
Fibrinolytic twice daily	Fibrinolytic twice daily	University of North Carolina, Chapel Hill	marketed	Fibrinolytic agent	Plasminogen / Fibrin
Fibrinolytic once daily	Fibrinolytic once daily	University of North Carolina, Chapel Hill	marketed	Fibrinolytic agent / Thrombolytic	Plasminogen / Fibrin
low-dose tenecteplase intravenous thrombolysis	low-dose tenecteplase intravenous thrombolysis	Southwest Hospital, China	marketed	Fibrinolytic agent / Tissue plasminogen activator (tPA)	Plasminogen / Fibrin
Intravenous Tenecteplase	Intravenous Tenecteplase	NHS Greater Glasgow and Clyde	phase 3	Fibrinolytic agent / Tissue plasminogen activator (tPA)	Plasminogen / Fibrin
rhPro-UK simulation agent	rhPro-UK simulation agent	Tasly Biopharmaceuticals Co., Ltd.	phase 3	Fibrinolytic agent / Thrombolytic	Plasminogen / Fibrin
Intravenous rhTNK-tPA	Intravenous rhTNK-tPA	Xinqiao Hospital of Chongqing	phase 3	Thrombolytic agent / Fibrinolytic	Plasminogen / Fibrin

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Fibrinolytic agent / Tissue plasminogen activator (tPA) class)

Central Hospital, Nancy, France · 1 drug in this class
Genentech, Inc. · 1 drug in this class
Hospital Clinic of Barcelona · 1 drug in this class
NHS Greater Glasgow and Clyde · 1 drug in this class
Southwest Hospital, China · 1 drug in this class
The George Institute · 1 drug in this class
University of Manitoba · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Intra-arterial infusion of Alteplase — Competitive Intelligence Brief. https://druglandscape.com/ci/intra-arterial-infusion-of-alteplase. Accessed 2026-05-17.

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