Who are Guafenesin tablets's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): DEXTROMETHORPHAN HYDROBROMIDE, Mucinex, Ivy Leaves Cough Liquid, Dextromethorphan hydrobromide with guaifenesin, Mucinex® SE, Guaifenesin Syrup.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Guafenesin tablets — Competitive Intelligence Brief

Guafenesin tablets (Guafenesin tablets) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Expectorant. Area: Respiratory.

marketed Expectorant Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Guafenesin tablets (Guafenesin tablets) — American Health Research. Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus in the airways.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Guafenesin tablets TARGET	Guafenesin tablets	American Health Research	marketed	Expectorant
DEXTROMETHORPHAN HYDROBROMIDE	DEXTROMETHORPHAN HYDROBROMIDE		marketed	Expectorant [EPC]		1984-01-01
Mucinex	guaifenesin	Generic (multiple manufacturers)	marketed	Expectorant [EPC]	Vagal gastric reflex → increased respiratory secretions	1952-01-01
Ivy Leaves Cough Liquid	Ivy Leaves Cough Liquid	Engelhard Arzneimittel GmbH & Co.KG	marketed	Herbal expectorant
Dextromethorphan hydrobromide with guaifenesin	Dextromethorphan hydrobromide with guaifenesin	Washington University School of Medicine	marketed	Antitussive/expectorant combination	Sigma-1 receptor, NMDA receptor (dextromethorphan); non-specific expectorant mechanism (guaifenesin)
Mucinex® SE	Mucinex® SE	Reckitt Benckiser Inc.	marketed	Expectorant
Guaifenesin Syrup	Guaifenesin Syrup	Liaoning University of Traditional Chinese Medicine	marketed	Expectorant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Expectorant class)

Reckitt Benckiser LLC · 2 drugs in this class
American Health Research · 1 drug in this class
EMS · 1 drug in this class
Guang'anmen Hospital of China Academy of Chinese Medical Sciences · 1 drug in this class
Liaoning University of Traditional Chinese Medicine · 1 drug in this class
Reckitt Benckiser Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Guafenesin tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/guafenesin-tablets. Accessed 2026-05-14.

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