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Guafenesin tablets

American Health Research · FDA-approved active Small molecule

Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus in the airways.

Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus in the airways. Used for Productive cough due to common cold, flu, or other respiratory conditions.

At a glance

Generic nameGuafenesin tablets
Also known asMucinex®
SponsorAmerican Health Research
Drug classExpectorant
ModalitySmall molecule
Therapeutic areaRespiratory
PhaseFDA-approved

Mechanism of action

Guaifenesin is an expectorant that works by thinning mucus secretions in the respiratory tract, making them less viscous and easier to expectorate. It is thought to act by increasing the water content of respiratory secretions, thereby reducing mucus thickness and facilitating clearance through coughing. This mechanism helps relieve chest congestion associated with colds, flu, and other respiratory conditions.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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