{"id":"guafenesin-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Rash"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Guaifenesin is an expectorant that works by thinning mucus secretions in the respiratory tract, making them less viscous and easier to expectorate. It is thought to act by increasing the water content of respiratory secretions, thereby reducing mucus thickness and facilitating clearance through coughing. This mechanism helps relieve chest congestion associated with colds, flu, and other respiratory conditions.","oneSentence":"Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus in the airways.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:40:03.964Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Productive cough due to common cold, flu, or other respiratory conditions"}]},"trialDetails":[{"nctId":"NCT05843669","phase":"PHASE4","title":"A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis.","status":"COMPLETED","sponsor":"American Health Research","startDate":"2023-07-17","conditions":"Chronic Bronchitis","enrollment":82}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Mucinex®"],"phase":"marketed","status":"active","brandName":"Guafenesin tablets","genericName":"Guafenesin tablets","companyName":"American Health Research","companyId":"american-health-research","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus in the airways. Used for Productive cough due to common cold, flu, or other respiratory conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}