glutamine combined with thalidomide — Competitive Intelligence Brief

glutamine combined with thalidomide (glutamine combined with thalidomide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Immunomodulator. Area: Oncology.

phase 3 Immunomodulator Oncology Small molecule

Target snapshot

glutamine combined with thalidomide (glutamine combined with thalidomide) — Air Force Military Medical University, China. Glutamine has been shown to have immunomodulatory effects, while thalidomide is known for its antiangiogenic and immunomodulatory properties.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
glutamine combined with thalidomide TARGET	glutamine combined with thalidomide	Air Force Military Medical University, China	phase 3	Immunomodulator
Ixazomib plus low-dose lenalidomide	Ixazomib plus low-dose lenalidomide	Second Affiliated Hospital, School of Medicine, Zhejiang University	marketed	Proteasome inhibitor and immunomodulatory agent	Proteasome and cereblon
FTY720	FTY720	Novartis Pharmaceuticals	marketed	Sphingosine-1-phosphate receptor modulator; Immunomodulator	Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5)
bee venom	bee venom	Assistance Publique - Hôpitaux de Paris	marketed	Natural product immunomodulator
Korean Red Ginseng (KRG)	Korean Red Ginseng (KRG)	Pusan National University Hospital	marketed	Herbal adaptogen / immunomodulator
Chloroquine prophylaxis	Chloroquine prophylaxis	Radboud University Medical Center	marketed	Antimalarial; immunomodulator	Plasmodium falciparum heme detoxification pathway; toll-like receptors
PF-06863135 + lenalidomide	pf-06863135-lenalidomide	Pfizer	marketed	small molecule + immunomodulatory drug	unknown

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Immunomodulator class)

1. Actavis Mid-Atlantic LLC · 1 drug in this class
2. Active Biotech AB · 1 drug in this class
3. Air Force Military Medical University, China · 1 drug in this class
4. Astellas Pharma Inc · 1 drug in this class
5. Bayer · 1 drug in this class
6. Beijing Children's Hospital · 1 drug in this class
7. Cancer Institute and Hospital, Chinese Academy of Medical Sciences · 1 drug in this class
8. Centro de Investigaciones Medicas y Ensayos Clinicos Dr Italo Fabbri · 1 drug in this class
9. Chang Gung Memorial Hospital · 1 drug in this class
10. ALK-Abelló A/S · 1 drug in this class