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generic bupropion — Competitive Intelligence Brief
marketed
Norepinephrine-dopamine reuptake inhibitor (NDRI)
Norepinephrine transporter (NET); Dopamine transporter (DAT)
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
generic bupropion (generic bupropion) — University of Michigan. Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI) that increases levels of norepinephrine and dopamine in the brain by blocking their reuptake at the presynaptic neuron.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| generic bupropion TARGET | generic bupropion | University of Michigan | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET); Dopamine transporter (DAT) | |
| bupropion extra long (XL) | bupropion extra long (XL) | New York State Psychiatric Institute | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET), dopamine transporter (DAT) | |
| Welbutrin XL | Welbutrin XL | Massachusetts General Hospital | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET) and dopamine transporter (DAT) | |
| Switch to bupropion | Switch to bupropion | Centre for Addiction and Mental Health | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET); Dopamine transporter (DAT) | |
| BuproprionSR | BuproprionSR | National Institute of Mental Health (NIMH) | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET) and dopamine transporter (DAT) | |
| Bupropion XL 300 | Bupropion XL 300 | Washington University School of Medicine | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET), Dopamine transporter (DAT) | |
| Active bupropion-Placebo gum | Active bupropion-Placebo gum | University of Wisconsin, Madison | marketed | Norepinephrine-dopamine reuptake inhibitor (NDRI) | Norepinephrine transporter (NET) and dopamine transporter (DAT) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Norepinephrine-dopamine reuptake inhibitor (NDRI) class)
- University of Wisconsin, Madison · 2 drugs in this class
- Massachusetts General Hospital · 1 drug in this class
- National Institute of Mental Health (NIMH) · 1 drug in this class
- New York State Psychiatric Institute · 1 drug in this class
- University of Michigan · 1 drug in this class
- University of Rochester NCORP Research Base · 1 drug in this class
- University of Texas Southwestern Medical Center · 1 drug in this class
- Centre for Addiction and Mental Health · 1 drug in this class
- Washington University School of Medicine · 1 drug in this class
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Cite this brief
Drug Landscape (2026). generic bupropion — Competitive Intelligence Brief. https://druglandscape.com/ci/generic-bupropion. Accessed 2026-05-13.
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