Exparel Injectable Solution — Competitive Intelligence Brief

Exparel Injectable Solution (Exparel Injectable Solution) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (liposomal formulation). Area: Pain Management / Anesthesia.

marketed Local anesthetic (liposomal formulation) Voltage-gated sodium channels Pain Management / Anesthesia Small molecule

Target snapshot

Exparel Injectable Solution (Exparel Injectable Solution) — The Cooper Health System. Liposomal bupivacaine is an encapsulated local anesthetic that blocks nerve impulses by inhibiting sodium channel activity, providing prolonged pain relief after surgical procedures.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Exparel Injectable Solution TARGET	Exparel Injectable Solution	The Cooper Health System	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Hyperbaric Bupivicaine	Hyperbaric Bupivicaine	University of Witwatersrand, South Africa	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Hyperbaric Prilocaine 1%	Hyperbaric Prilocaine 1%	Dr. Pere Roura-Poch	marketed	Local anesthetic	Voltage-gated sodium channels
Brand lamotrigine	Brand lamotrigine	University of Maryland, Baltimore	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Lidocaïne 2%	Lidocaïne 2%	University of Liege	marketed	Local anesthetic	Voltage-gated sodium channels
Lamotrigine generic "B"	Lamotrigine generic "B"	University of Cincinnati	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition
Liposomal bupivacaine left injection	Liposomal bupivacaine left injection	Prisma Health-Upstate	marketed	Local anesthetic (amide)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (liposomal formulation) class)

1. Pacira Pharmaceuticals, Inc · 4 drugs in this class
2. Huazhong University of Science and Technology · 1 drug in this class
3. Maimonides Medical Center · 1 drug in this class
4. The Cleveland Clinic · 1 drug in this class
5. The Cooper Health System · 1 drug in this class
6. The University of Texas Health Science Center, Houston · 1 drug in this class
7. Tianjin Medical University General Hospital · 1 drug in this class
8. University of California, Davis · 1 drug in this class
9. Catherine Vandepitte, M.D. · 1 drug in this class
10. Wake Forest University Health Sciences · 1 drug in this class