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Early Vasopressors — Competitive Intelligence Brief
phase 3
Sympathomimetic vasopressor
Alpha-1 and beta-1 adrenergic receptors
Critical Care / Intensive Care Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
Early Vasopressors (Early Vasopressors) — Massachusetts General Hospital. Early vasopressors are sympathomimetic agents that increase blood pressure and tissue perfusion by stimulating adrenergic receptors to counteract hypotension in critically ill patients.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Early Vasopressors TARGET | Early Vasopressors | Massachusetts General Hospital | phase 3 | Sympathomimetic vasopressor | Alpha-1 and beta-1 adrenergic receptors | |
| lidocaine + epinephrine 1:100,000 | lidocaine + epinephrine 1:100,000 | Weill Medical College of Cornell University | marketed | Local anesthetic with vasoconstrictor | Voltage-gated sodium channels (lidocaine); alpha-1 and beta-1 adrenergic receptors (epinephrine) | |
| Articaine / EPINEPHrine Cartridge | Articaine / EPINEPHrine Cartridge | Universidad de Antioquia | marketed | Local anesthetic with vasopressor | Voltage-gated sodium channels (articaine); alpha-1 and beta-1 adrenergic receptors (epinephrine) | |
| low-dose epinephrine and tranexamic acid | low-dose epinephrine and tranexamic acid | King Abdullah International Medical Research Center | marketed | Combination hemostatic and vasopressor agent | Alpha-1 and beta-1 adrenergic receptors (epinephrine); plasminogen and plasmin (tranexamic acid) | |
| Lidocaine plus adrenaline | Lidocaine plus adrenaline | University of Santiago de Compostela | marketed | Local anesthetic with vasopressor | Voltage-gated sodium channels; alpha-1 and beta-1 adrenergic receptors |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sympathomimetic vasopressor class)
- Massachusetts General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Early Vasopressors — Competitive Intelligence Brief. https://druglandscape.com/ci/early-vasopressors. Accessed 2026-05-16.
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