Dyclonine hydrochloride mucilage — Competitive Intelligence Brief

Dyclonine hydrochloride mucilage (Dyclonine hydrochloride mucilage) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain management / Otolaryngology.

marketed Local anesthetic Voltage-gated sodium channels Pain management / Otolaryngology Small molecule

Target snapshot

Dyclonine hydrochloride mucilage (Dyclonine hydrochloride mucilage) — Peking Union Medical College Hospital. Dyclonine hydrochloride is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Dyclonine hydrochloride mucilage TARGET	Dyclonine hydrochloride mucilage	Peking Union Medical College Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Ropivacaine 0,75% in PENG block	Ropivacaine 0,75% in PENG block	University of Liege	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Ropivacaine 0.2% for S-ESPB	Ropivacaine 0.2% for S-ESPB	Poznan University of Medical Sciences	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Bupivacaine Hcl 0.75% Inj	Bupivacaine Hcl 0.75% Inj	Rothman Institute Orthopaedics	marketed	Local anesthetic	Voltage-gated sodium channels
Fentanyl and bupivacaine	Fentanyl and bupivacaine	Hospital Central Dr. Luis Ortega	marketed	Opioid analgesic combined with local anesthetic	Mu opioid receptor (fentanyl); voltage-gated sodium channels (bupivacaine)
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
SUP Lidocaine	SUP Lidocaine	University of Michigan	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class