Last reviewed · How we verify

Atrial fibrillation — Treatment Landscape & Competitive Intelligence

Atrial fibrillation (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Atrial fibrillation, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Onoact LANDIOLOL Aop Hlth Us landiolol Beta-1 adrenergic receptor 2024-01-01
Multaq DRONEDARONE Sanofi Antiarrhythmic [EPC] Potassium voltage-gated channel subfamily KQT member 2 2009-01-01
Tikosyn DOFETILIDE Pfizer Antiarrhythmic [EPC] Potassium voltage-gated channel subfamily H member 2 1999-01-01
Plavix clopidogrel Generic (originally Sanofi/BMS) Thienopyridine antiplatelet agent Cytochrome P450 2B6, P2Y purinoceptor 12, Sodium-dependent serotonin transporter 1997-11-17
Zebeta BISOPROLOL Teva beta-Adrenergic Blocker Beta-1 adrenergic receptor 1992-01-01
Brevibloc In Plastic Container ESMOLOL Pfizer beta-Adrenergic Blocker Beta-1 adrenergic receptor 1986-01-01
Cardizem diltiazem Generic (originally Tanabe Seiyaku) Calcium channel blocker (non-dihydropyridine, benzothiazepine) Voltage-dependent calcium channel gamma-1 subunit, Multidrug resistance protein 1, Solute carrier family 22 member 1 1982-11-05
Acylanid ACETYLDIGITOXIN Novartis acetyldigitoxin Sodium/potassium-transporting ATPase 1975-01-01
Inderal propranolol Generic (originally ICI/AstraZeneca) Non-selective beta-blocker Nuclear receptor subfamily 2 group E member 1, 5-hydroxytryptamine receptor 6, Cytochrome P450 1A2 1967-11-13
Persantine DIPYRIDAMOLE Boehringer Ingelheim Platelet Aggregation Inhibitor [EPC] Equilibrative nucleoside transporter 1 1961-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Pfizer · 2 drugs in Atrial fibrillation
  2. Boehringer Ingelheim · 2 drugs in Atrial fibrillation
  3. · 2 drugs in Atrial fibrillation
  4. Bayer · 1 drug in Atrial fibrillation
  5. Eli Lilly · 1 drug in Atrial fibrillation
  6. Generic (originally Burroughs Wellcome/GSK) · 1 drug in Atrial fibrillation
  7. Generic (originally ICI/AstraZeneca) · 1 drug in Atrial fibrillation
  8. Generic (originally Sanofi/BMS) · 1 drug in Atrial fibrillation
  9. Generic (originally Tanabe Seiyaku) · 1 drug in Atrial fibrillation
  10. Novartis · 1 drug in Atrial fibrillation
  11. Sanofi · 1 drug in Atrial fibrillation
  12. Teva · 1 drug in Atrial fibrillation

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Atrial fibrillation:

Cite this brief

Drug Landscape (2026). Atrial fibrillation — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/atrial-fibrillation. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing