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DEXTROMETHORPHAN HYDROBROMIDE — Competitive Intelligence Brief
marketed
Expectorant [EPC]
Small molecule
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Target snapshot
DEXTROMETHORPHAN HYDROBROMIDE (DEXTROMETHORPHAN HYDROBROMIDE).
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DEXTROMETHORPHAN HYDROBROMIDE TARGET | DEXTROMETHORPHAN HYDROBROMIDE | marketed | Expectorant [EPC] | 1984-01-01 | ||
| Mucinex | guaifenesin | Generic (multiple manufacturers) | marketed | Expectorant [EPC] | Vagal gastric reflex → increased respiratory secretions | 1952-01-01 |
| Dextromethorphan hydrobromide with guaifenesin | Dextromethorphan hydrobromide with guaifenesin | Washington University School of Medicine | marketed | Antitussive/expectorant combination | Sigma-1 receptor, NMDA receptor (dextromethorphan); non-specific expectorant mechanism (guaifenesin) | |
| Ivy Leaves Cough Liquid | Ivy Leaves Cough Liquid | Engelhard Arzneimittel GmbH & Co.KG | marketed | Herbal expectorant | ||
| Mucinex® | Mucinex® | Reckitt Benckiser LLC | marketed | Expectorant | ||
| Guaifenesin Syrup | Guaifenesin Syrup | Liaoning University of Traditional Chinese Medicine | marketed | Expectorant | ||
| Guafenesin tablets | Guafenesin tablets | American Health Research | marketed | Expectorant |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Expectorant [EPC] class)
- · 1 drug in this class
- Generic (multiple manufacturers) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). DEXTROMETHORPHAN HYDROBROMIDE — Competitive Intelligence Brief. https://druglandscape.com/ci/dextromethorphan-hydrobromide. Accessed 2026-05-13.
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