Who are Cytotec (reference drug)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Cytotec, Misoprostol 400 Microgram Oral Tablet, preoperative vaginal misoprostol, Alprostadil ﹠control, Prostin (PGE2) tablets, low dose peroral misoprostol.

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Last reviewed 2026-06-10 · How we verify

Cytotec (reference drug) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cytotec (reference drug) (Cytotec (reference drug)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Prostaglandin E1 analog. Area: Gastroenterology.

marketed Prostaglandin E1 analog Prostaglandin E receptor (EP receptor) Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Cytotec (reference drug) (Cytotec (reference drug)) — Dong-A ST Co., Ltd.. Cytotec (misoprostol) is a prostaglandin E1 analog that reduces gastric acid secretion and protects the gastric mucosa.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Cytotec (reference drug) TARGET	Cytotec (reference drug)	Dong-A ST Co., Ltd.	marketed	Prostaglandin E1 analog	Prostaglandin E receptor (EP receptor)
Cytotec	misoprostol	Generic (originally Searle/Pfizer)	marketed	Prostaglandin E1 analog	Prostaglandin E2 receptor EP2 subtype, Prostaglandin E2 receptor EP3 subtype, Prostaglandin E2 receptor EP4 subtype	1988-12-27
Misoprostol 400 Microgram Oral Tablet	Misoprostol 400 Microgram Oral Tablet	Assuta Ashdod Hospital	marketed	Prostaglandin E1 analogue	Prostaglandin E receptor (EP receptor)
preoperative vaginal misoprostol	preoperative vaginal misoprostol	Ain Shams Maternity Hospital	marketed	Prostaglandin E1 analogue	Prostaglandin E receptor (EP receptor)
Alprostadil ﹠control	Alprostadil ﹠control	Shanghai 10th People's Hospital	marketed	Prostaglandin E1 analog	Prostanoid receptors (EP receptors)
Prostin (PGE2) tablets	Prostin (PGE2) tablets	Wolfson Medical Center	marketed	Prostaglandin E1 analog	Prostaglandin E receptors (EP1, EP2, EP3, EP4)
low dose peroral misoprostol	low dose peroral misoprostol	University Medical Centre Ljubljana	marketed	Prostaglandin E1 analogue	Prostaglandin E receptor (EP receptor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Prostaglandin E1 analog class)

Dong-A ST Co., Ltd. · 1 drug in this class
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia · 1 drug in this class
Generic (originally Searle/Pfizer) · 1 drug in this class
Shanghai 10th People's Hospital · 1 drug in this class
West China Hospital · 1 drug in this class
Wolfson Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cytotec (reference drug) — Competitive Intelligence Brief. https://druglandscape.com/ci/cytotec-reference-drug. Accessed 2026-06-10.

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