Who are Comparator: paroxetine HCL's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lexapro, Prozac, SSRI antidepressants, SSRI (SEROPLEX ou ZOLOFT), Zoloft tablets, sertraline fluvoxamine.

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Last reviewed 2026-05-14 · How we verify

Comparator: paroxetine HCL — Competitive Intelligence Brief

Comparator: paroxetine HCL (Comparator: paroxetine HCL) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective serotonin reuptake inhibitor (SSRI). Area: Psychiatry / Neurology.

phase 3 Selective serotonin reuptake inhibitor (SSRI) Serotonin transporter (SERT) Psychiatry / Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Comparator: paroxetine HCL (Comparator: paroxetine HCL) — Merck Sharp & Dohme LLC. Paroxetine HCl selectively inhibits the reuptake of serotonin at the neuronal synapse, increasing serotonin availability in the brain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Comparator: paroxetine HCL TARGET	Comparator: paroxetine HCL	Merck Sharp & Dohme LLC	phase 3	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
Lexapro	escitalopram	Generic (originally Lundbeck/Forest)	marketed	Selective Serotonin Reuptake Inhibitor (SSRI)	Serotonin (5-HT) reuptake transporter	2002-08-14
Prozac	fluoxetine	Eli Lilly and Company	marketed	Selective Serotonin Reuptake Inhibitor (SSRI)	Serotonin reuptake transporter	1987-12-29
SSRI antidepressants	SSRI antidepressants	Nanjing Medical University	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
SSRI (SEROPLEX ou ZOLOFT)	SSRI (SEROPLEX ou ZOLOFT)	Centre Hospitalier Universitaire Dijon	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
Zoloft tablets	Zoloft tablets	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
sertraline fluvoxamine	sertraline fluvoxamine	Second Affiliated Hospital, School of Medicine, Zhejiang University	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective serotonin reuptake inhibitor (SSRI) class)

University of Texas Southwestern Medical Center · 3 drugs in this class
Johns Hopkins University · 2 drugs in this class
GlaxoSmithKline · 2 drugs in this class
Daiichi Sankyo Co., Ltd. · 1 drug in this class
Guangdong Provincial People's Hospital · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Massachusetts General Hospital · 1 drug in this class
Fundació Sant Joan de Déu · 1 drug in this class
Centre Hospitalier Universitaire Dijon · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Comparator: paroxetine HCL — Competitive Intelligence Brief. https://druglandscape.com/ci/comparator-paroxetine-hcl. Accessed 2026-05-14.

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