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clonidine gel 1% — Competitive Intelligence Brief
phase 3
Alpha-2 adrenergic agonist
Alpha-2 adrenergic receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
clonidine gel 1% (clonidine gel 1%) — Irmandade da Santa Casa de Misericordia de Sao Paulo. Clonidine is an alpha-2 adrenergic agonist that decreases sympathetic nervous system activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| clonidine gel 1% TARGET | clonidine gel 1% | Irmandade da Santa Casa de Misericordia de Sao Paulo | phase 3 | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Low-dose Dexmedetomidine | Low-dose Dexmedetomidine | Tang-Du Hospital | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Dexmedetomidine 0.5μg/kg | Dexmedetomidine 0.5μg/kg | Eye & ENT Hospital of Fudan University | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Intraoperative infusion of dexmedetomidine | Intraoperative infusion of dexmedetomidine | Nanjing First Hospital, Nanjing Medical University | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Butorphanol and dexmedetomindine | Butorphanol and dexmedetomindine | The Affiliated Hospital of Qingdao University | marketed | Opioid agonist-antagonist combined with alpha-2 adrenergic agonist | Opioid receptors (kappa, sigma, mu) and alpha-2 adrenergic receptors | |
| dexmedetomidine 80 µg | dexmedetomidine 80 µg | Fayoum University Hospital | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Sufentanil and dexmedetomidine | Sufentanil and dexmedetomidine | Obstetrics & Gynecology Hospital of Fudan University | marketed | Opioid agonist and alpha-2 adrenergic agonist combination | Mu opioid receptor and alpha-2 adrenergic receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-2 adrenergic agonist class)
- USWM, LLC (dba US WorldMeds) · 2 drugs in this class
- China International Neuroscience Institution · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- Eye Therapies, LLC · 1 drug in this class
- Galderma R&D · 1 drug in this class
- Guangzhou Women and Children's Medical Center · 1 drug in this class
- Derm Research, PLLC · 1 drug in this class
- Irmandade da Santa Casa de Misericordia de Sao Paulo · 1 drug in this class
- KK Women's and Children's Hospital · 1 drug in this class
- American University of Beirut Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). clonidine gel 1% — Competitive Intelligence Brief. https://druglandscape.com/ci/clonidine-gel-1. Accessed 2026-05-17.
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