Bupivacaine liposomal injectable suspension — Competitive Intelligence Brief

Bupivacaine liposomal injectable suspension (Bupivacaine liposomal injectable suspension) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (liposomal formulation). Area: Anesthesia/Pain Management.

marketed Local anesthetic (liposomal formulation) Voltage-gated sodium channels Anesthesia/Pain Management Small molecule

Target snapshot

Bupivacaine liposomal injectable suspension (Bupivacaine liposomal injectable suspension) — The University of Texas Health Science Center, Houston. Bupivacaine liposomal injectable suspension is a local anesthetic that blocks sodium channels in nerve cell membranes, with prolonged duration of action due to encapsulation in liposomes.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine liposomal injectable suspension TARGET	Bupivacaine liposomal injectable suspension	The University of Texas Health Science Center, Houston	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Articaine Hydrochloride + Epinephrine	Articaine Hydrochloride + Epinephrine	Ankara Yildirim Beyazıt University	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-1 adrenergic receptors (epinephrine component)
Synera(TM)	Synera(TM)	IWK Health Centre	marketed	Topical local anesthetic	Voltage-gated sodium channels
Ropivacaine + Ketamine	Ropivacaine + Ketamine	Aga Khan University	marketed	Local anesthetic + NMDA receptor antagonist combination	Voltage-gated sodium channels (ropivacaine); NMDA receptor (ketamine)
Paroxetine+Lamotrigine	Paroxetine+Lamotrigine	Ministry of Health & Welfare, Korea	marketed	SSRI + anticonvulsant mood stabilizer combination	Serotonin transporter (SERT); voltage-gated sodium channels; glutamate release modulation
Dose of prilocaine	Dose of prilocaine	Hospital General Universitario Gregorio Marañon	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Buffered Articaine Hydrochloride + Epinephrine	Buffered Articaine Hydrochloride + Epinephrine	Ohio State University	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-1 adrenergic receptors (epinephrine component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (liposomal formulation) class)

1. Pacira Pharmaceuticals, Inc · 4 drugs in this class
2. Huazhong University of Science and Technology · 1 drug in this class
3. Maimonides Medical Center · 1 drug in this class
4. The Cleveland Clinic · 1 drug in this class
5. The Cooper Health System · 1 drug in this class
6. The University of Texas Health Science Center, Houston · 1 drug in this class
7. Tianjin Medical University General Hospital · 1 drug in this class
8. University of California, Davis · 1 drug in this class
9. Catherine Vandepitte, M.D. · 1 drug in this class
10. Wake Forest University Health Sciences · 1 drug in this class