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Brimonidine Tartrate Gel — Competitive Intelligence Brief
phase 2
Alpha-2 adrenergic agonist
Alpha-2 adrenergic receptor
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Brimonidine Tartrate Gel (Brimonidine Tartrate Gel) — LEO Pharma. Brimonidine tartrate gel works by reducing the amount of norepinephrine in the body, which helps to decrease redness and swelling in the skin.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Brimonidine Tartrate Gel TARGET | Brimonidine Tartrate Gel | LEO Pharma | phase 2 | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Dexmetomidine intravenously | Dexmetomidine intravenously | KAT General Hospital | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Dexmedetomidine 0.5μg/kg | Dexmedetomidine 0.5μg/kg | Eye & ENT Hospital of Fudan University | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Brinzolamide/Brimonidine FC | Brinzolamide/Brimonidine FC | University Hospital of Patras | marketed | Carbonic anhydrase inhibitor / Alpha-2 adrenergic agonist combination | Carbonic anhydrase II; Alpha-2 adrenergic receptor | |
| ropivacaine mixed with dexmedetomidine | ropivacaine mixed with dexmedetomidine | The First Hospital of Qinhuangdao | marketed | Local anesthetic combination with alpha-2 adrenergic agonist | Voltage-gated sodium channels (ropivacaine); alpha-2 adrenergic receptors (dexmedetomidine) | |
| Low-dose Dexmedetomidine | Low-dose Dexmedetomidine | Tang-Du Hospital | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Combigan Two Times Daily (BID) | Combigan Two Times Daily (BID) | Cornerstone Health Care, PA | marketed | Fixed-dose combination of alpha-2 adrenergic agonist and beta-blocker | Alpha-2 adrenergic receptor; beta-1 and beta-2 adrenergic receptors |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-2 adrenergic agonist class)
- USWM, LLC (dba US WorldMeds) · 2 drugs in this class
- China International Neuroscience Institution · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- Eye Therapies, LLC · 1 drug in this class
- Galderma R&D · 1 drug in this class
- Guangzhou Women and Children's Medical Center · 1 drug in this class
- Derm Research, PLLC · 1 drug in this class
- Irmandade da Santa Casa de Misericordia de Sao Paulo · 1 drug in this class
- KK Women's and Children's Hospital · 1 drug in this class
- American University of Beirut Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Brimonidine Tartrate Gel — Competitive Intelligence Brief. https://druglandscape.com/ci/brimonidine-tartrate-gel. Accessed 2026-05-16.
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