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Brimonidine Tartrate Gel
Brimonidine tartrate gel works by reducing the amount of norepinephrine in the body, which helps to decrease redness and swelling in the skin.
Brimonidine tartrate gel works by reducing the amount of norepinephrine in the body, which helps to decrease redness and swelling in the skin. Used for Treatment of erythema associated with rosacea.
At a glance
| Generic name | Brimonidine Tartrate Gel |
|---|---|
| Sponsor | LEO Pharma |
| Drug class | Alpha-2 adrenergic agonist |
| Target | Alpha-2 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 2 |
Mechanism of action
Brimonidine tartrate gel is an alpha-2 adrenergic agonist that decreases the production of norepinephrine, a neurotransmitter that can cause blood vessels to dilate and increase blood flow to the skin. By reducing norepinephrine levels, brimonidine tartrate gel helps to decrease redness and swelling in the skin, making it a useful treatment for conditions such as rosacea.
Approved indications
- Treatment of erythema associated with rosacea
Common side effects
- Dry mouth
- Headache
- Fatigue
Key clinical trials
- Brimonidine 0.33% for Rosacea-Related Facial Erythema (PHASE4)
- Safety and Efficacy Study of TAR-0520 Gel in Prevention of Taxane-induced Peripheral Neuropathy (PHASE2)
- TAR-0520 Gel in EGFR Inhibitor-induced Folliculitis (PHASE2)
- Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea (NA)
- Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea (PHASE3)
- Mirvaso in Use Study (PHASE4)
- Brimonidine in Rosacea (NA)
- Comparative Safety and Efficacy of Two Rosacea Products in the Treatment of Facial Erythema of Rosacea (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Brimonidine Tartrate Gel CI brief — competitive landscape report
- Brimonidine Tartrate Gel updates RSS · CI watch RSS
- LEO Pharma portfolio CI