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Benzidamine — Competitive Intelligence Brief
phase 3
benzydamine
Soluble guanylate cyclase
Pain
Small molecule
Live · refreshed every 30 min
Target snapshot
Benzidamine (BENZYDAMINE). Benzidamine works by activating soluble guanylate cyclase, an enzyme that produces cyclic guanosine monophosphate (cGMP), leading to pain relief.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Benzidamine TARGET | BENZYDAMINE | phase 3 | benzydamine | Soluble guanylate cyclase | ||
| Inomax | NITRIC OXIDE | Vero Biotech Inc | marketed | Standardized Chemical Allergen [EPC] | Soluble guanylate cyclase | 1999-01-01 |
| Topical Nitroglycerine | Topical Nitroglycerine | Aultman Health Foundation | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| Inhaled Nitric Oxide (iNO) use | Inhaled Nitric Oxide (iNO) use | The University of Texas Health Science Center, Houston | marketed | Inhaled vasodilator | Soluble guanylate cyclase | |
| nadolol + ISMN | nadolol + ISMN | E-DA Hospital | marketed | Beta-blocker + Nitrate combination | Beta-adrenergic receptors (nadolol); soluble guanylate cyclase (ISMN) | |
| Nitroglycerin patch | Nitroglycerin patch | GF Strong Rehabilitation Centre | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| Nitroglycerin (NTG) | Nitroglycerin (NTG) | Bristol-Myers Squibb | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
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Sponsor landscape (benzydamine class)
- · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Benzidamine — Competitive Intelligence Brief. https://druglandscape.com/ci/benzydamine. Accessed 2026-06-10.
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