Who are Arm 1: CL-H1T's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): BENZHYDROCODONE, NALBUPHINE HYDROCHLORIDE, XR-NTX 380 mg, intramuscular injection, opioid pain pills, Standard Opioid, Opioid group.

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Last reviewed 2026-05-16 · How we verify

Arm 1: CL-H1T — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Arm 1: CL-H1T (Arm 1: CL-H1T) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: kappa opioid receptor agonist. Area: Pain.

phase 2 kappa opioid receptor agonist kappa opioid receptor Pain Small molecule Live · refreshed every 30 min

Target snapshot

Arm 1: CL-H1T (Arm 1: CL-H1T) — Charleston Laboratories, Inc. CL-H1T is a compound that targets the kappa opioid receptor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Arm 1: CL-H1T TARGET	Arm 1: CL-H1T	Charleston Laboratories, Inc	phase 2	kappa opioid receptor agonist	kappa opioid receptor
BENZHYDROCODONE	BENZHYDROCODONE		marketed	Opioid analgesic combination; full mu-opioid agonist with non-opioid analgesic	Mu-opioid receptors (primary); delta and kappa opioid receptors (secondary); central nervous system pain pathways	2018-01-01
NALBUPHINE HYDROCHLORIDE	NALBUPHINE HYDROCHLORIDE		marketed		kappa opioid receptors, mu opioid receptors	1979-01-01
XR-NTX 380 mg, intramuscular injection	XR-NTX 380 mg, intramuscular injection	University of Pennsylvania	marketed	Opioid receptor antagonist	Mu opioid receptor (primary); delta and kappa opioid receptors
opioid pain pills	opioid pain pills	Rush University Medical Center	marketed	Opioid analgesic	Mu opioid receptor (primary); delta and kappa opioid receptors (secondary)
Standard Opioid	Standard Opioid	Prisma Health-Upstate	marketed	Opioid analgesic	Mu opioid receptor (primary); delta and kappa opioid receptors (secondary)
Opioid group	Opioid group	Beijing Friendship Hospital	marketed	Opioid agonist	Mu opioid receptor (primary), delta opioid receptor, kappa opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (kappa opioid receptor agonist class)

Charleston Laboratories, Inc · 1 drug in this class
TWi Biotechnology, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Arm 1: CL-H1T — Competitive Intelligence Brief. https://druglandscape.com/ci/arm-1-cl-h1t. Accessed 2026-05-16.

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