Last reviewed · How we verify
aprotinin or tranexamic acid — Competitive Intelligence Brief
phase 3
Antifibrinolytic
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
aprotinin or tranexamic acid (aprotinin or tranexamic acid) — German Heart Center. Tranexamic acid works by inhibiting the activation of plasminogen to plasmin, thereby reducing fibrinolysis and preventing excessive bleeding.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| aprotinin or tranexamic acid TARGET | aprotinin or tranexamic acid | German Heart Center | phase 3 | Antifibrinolytic | ||
| Trasylol | APROTININ | Bayer | marketed | Antifibrinolytic Agent | Plasminogen | 1993-01-01 |
| Cyklokapron | TRANEXAMIC ACID | Exela Pharma | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1986-01-01 |
| Amicar | AMINOCAPROIC ACID | Epic Pharma Llc | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1964-01-01 |
| IV TXA | IV TXA | Massachusetts General Hospital | marketed | Antifibrinolytic agent | Plasminogen / Plasmin | |
| Tranexamic Acid Irrigation | Tranexamic Acid Irrigation | University of Wisconsin, Madison | marketed | Antifibrinolytic agent | Plasminogen / Plasmin | |
| Tranexamic Acid Injectable Solution | Tranexamic Acid Injectable Solution | Mount Sinai Hospital, Canada | marketed | Antifibrinolytic agent | Plasminogen / Plasmin |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifibrinolytic class)
- Ain Shams University · 1 drug in this class
- Bayer · 1 drug in this class
- German Heart Center · 1 drug in this class
- Institut Kassab d'Orthopédie · 1 drug in this class
- Miller Orthopedic Specialists · 1 drug in this class
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Cite this brief
Drug Landscape (2026). aprotinin or tranexamic acid — Competitive Intelligence Brief. https://druglandscape.com/ci/aprotinin-or-tranexamic-acid. Accessed 2026-05-17.
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