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NCT07429578: NewWaves
Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study
NA trial testing Transcranial Alternating Current Stimulation (tACS) in Generalized Anxiety Disorder (GAD) in 30 participants. Currently enrolling.
31 January 2026
Quick facts
| Lead sponsor | University of Sao Paulo |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 June 2025 |
| Primary completion | 31 January 2026 |
| Estimated completion | 31 May 2026 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Transcranial Alternating Current Stimulation (tACS)
Conditions studied
- Generalized Anxiety Disorder (GAD) — all drugs for Generalized Anxiety Disorder (GAD) →
- Chronic Insomnia — all drugs for Chronic Insomnia →
Sponsor
University of Sao Paulo
Who can join
Adults 18 to 65, any sex, with Generalized Anxiety Disorder (GAD) or Chronic Insomnia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an open-label pilot clinical trial to evaluate the effects of transcranial alternating current stimulation (tACS) in adults diagnosed with generalized anxiety disorder (GAD) and chronic primary insomnia. The study will involve 30 participants who will receive 20 sessions of tACS over four weeks. The stimulation will be delivered at 15 mA and 77.5 Hz using the Nexalin device. The main goal is to assess improvements in anxiety and sleep quality. Results from this study will provide preliminary evidence for future randomized controlled trials.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07429578
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07429578 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
- Last refreshed: 24 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07429578.
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