Last reviewed · How we verify
NCT07347509: CST-SP
Acute Effects of BCAA and L-Arginine on Performance in Elite Soccer Players
NA trial testing BCAA in Ergogenic Support and Performance in 21 participants. Completed in 15 September 2025.
12 June 2025
Quick facts
| Lead sponsor | Ataturk University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 21 |
| Start date | 10 January 2025 |
| Primary completion | 12 June 2025 |
| Estimated completion | 15 September 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- BCAA — full drug profile →
- L-Arginine — full drug profile →
- bcaa and l arginine
Conditions studied
- Ergogenic Support and Performance — all drugs for Ergogenic Support and Performance →
Sponsor
Ataturk University
Who can join
Adults 19 to 19, male only, with Ergogenic Support and Performance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
his study aims to investigate the acute effects of a single pre-exercise dose of branched-chain amino acids (BCAA) and L-arginine supplementation on anaerobic performance, sprint speed, agility, lactate response, and post-exercise heart rate recovery in male football players competing in a youth development league. Twenty-one football players participating in the T.F.F. U-19 Development League will be randomly assigned to one of three groups: BCAA (n = 7), L-arginine (n = 7), or placebo (n = 7). Participants will receive either 12 g of BCAA (4:1:1), 5 g of L-arginine, or an equivalent amount of maltodextrin, administered 1.5 hours before training. Performance assessments will include 10 m and 20 m sprint tests, an agility test, the Wingate anaerobic power test, blood lactate measurements, and post-exercise heart rate recovery measurements taken at the 1st, 3rd, and 5th minutes of recovery. Data will be analyzed using repeated measures analysis of variance to examine within- and between-group differences.Data obtained from the study were analyzed using the JASP 0.95.4 software. Pre-test and post-test values of the experimental and control groups were evaluated using Repeated Measures ANOVA. Effect size was determined using Eta Squared (η²), and differences between groups were identified using Tukey post hoc analysis. A 95% confidence interval was applied, and statistical significance was accepted at p \< 0.05. In the BCAA group, 20 m sprint performance (p \< 0.05) and agility test results (p \< 0.05) improved significantly compared to the control group. Additionally, heart rate recovery at the 3rd and 5th minutes was significantly faster in the BCAA group compared to both the L-arginine and placebo groups (p \< 0.05). In the L-arginine group, no significant improvements were observed in sprint performance, agility, lactate response, or Wingate parameters compared to placebo. No significant differences were found between groups in lactate response or anaerobic power variables (peak, mean, and minimum power, and fatigue index) (p \> 0.05). A single dose of BCAA supplementation improves short-distance sprint performance, agility, and heart rate recovery in football players; however, it does not have a significant effect on anaerobic power or lactate response. Acute L-arginine supplementation did not produce a significant ergogenic effect on these parameters. The findings suggest that amino acid supplementation may produce more pronounced effects with chronic rather than acute application
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07347509
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of BCAA
Trials testing the same drug.
- NCT05324475 — Maintaining Immune and Mitochondrial Functions in Old Adults With SAfe Nutrition. · NA · recruiting
- NCT06340399 — BCAA in Patients Undergoing Gastric Cancer Surgery · NA · not yet recruiting
- NCT06167772 — Leucine-enriched Branched-chain Amino Acid on Muscle Thickness, Interleukin-6, SOFA Score in Critical Illness · NA · completed
- NCT05729438 — Nutritional Assesment in Patients With Cirrhosis · recruiting
- NCT05484661 — Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults · NA · completed
Other Ataturk University trials
Trials by the same sponsor.
- NCT07518537 — Bulk-Fill Composite Restorations: Clinical Evaluation · NA · not yet recruiting
- NCT07241156 — Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression · NA · not yet recruiting
- NCT07451418 — The Effect of Mindfulness Compassionate Living Training on Unwanted Pregnancies · NA · not yet recruiting
- NCT07464548 — Effects of Stoma Education on Patients · NA · recruiting
- NCT07375277 — Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07347509 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ataturk University
- Last refreshed: 16 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07347509.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing