NCT07214467 (aDBS OUD) is a NA clinical trial of Deep Brain Stimulation in Substance Use Disorder (SUD), sponsored by University of California, San Francisco.

Who is sponsoring NCT07214467?

NCT07214467 is sponsored by University of California, San Francisco.

What drugs are being tested in NCT07214467?

Interventions in NCT07214467: Deep Brain Stimulation.

What condition does NCT07214467 study?

NCT07214467 studies Substance Use Disorder (SUD), Opioid Use Disorder (OUD).

Is NCT07214467 still recruiting?

NCT07214467 is currently recruiting now. Last updated 28 October 2025.

Last reviewed 2025-10-28 · How we verify

NCT07214467: aDBS OUD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

Recruiting now NA Last updated 28 October 2025

What this trial tests

NA trial testing Deep Brain Stimulation in Substance Use Disorder (SUD) in 6 participants. Currently enrolling.

Timeline

24 October 2025

Primary endpoint
22 November 2031

22 November 2031

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	treatment
Enrollment	6
Start date	24 October 2025
Primary completion	22 November 2031
Estimated completion	22 November 2031
Sites	1 location across United States

Drugs / interventions tested

Deep Brain Stimulation

Conditions studied

Substance Use Disorder (SUD) — all drugs for Substance Use Disorder (SUD) →
Opioid Use Disorder (OUD) — all drugs for Opioid Use Disorder (OUD) →

Sponsor

University of California, San Francisco

Who can join

Adults 22 to 75, any sex, with Substance Use Disorder (SUD) or Opioid Use Disorder (OUD). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine if personalized (adaptive) Deep Brain Stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes like reductions in craving and opioid use.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Deep Brain Stimulation

Trials testing the same drug.

NCT06924086 — The Children's Adaptive Deep Brain Stimulation for Epilepsy Trial · NA · recruiting
NCT07369401 — Deep Brain Stimulation of the Nucleus Accumbens and Anterior Limb of the Internal Capsule in the Treatment of Refractory · NA · not yet recruiting
NCT06991335 — VC/VS for Apathy in PD · NA · not yet recruiting
NCT07049003 — Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor · Phase 1 · recruiting
NCT07216222 — K08 VR Fear Conditioning · NA · enrolling by invitation

Other recruiting trials for Substance Use Disorder (SUD)

Currently open trials in the same condition.

NCT07278427 — Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START · recruiting
NCT07503067 — Identifying Substance Use Consequences · recruiting
NCT06790641 — Pathways to Perinatal Mental Health Equity · NA · recruiting
NCT07433985 — California MEPS Hub · NA · recruiting
NCT06794983 — Calls and Coordination for Transitions of Care at Re-entry · NA · recruiting

Other University of California, San Francisco trials

Trials by the same sponsor.

NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07214467 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
Last refreshed: 28 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07214467.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing