NCT05284773

Screening for Acute Malnutrition

Withdrawn NA Last updated 19 September 2024

What this trial tests

NA trial testing Caretaker MUAC screening - training by health workers in Acute Malnutrition in Childhood. Withdrawn.

Timeline

15 February 2030

Primary endpoint
10 March 2035

10 March 2035

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Start date	15 February 2030
Primary completion	10 March 2035
Estimated completion	10 March 2035

Drugs / interventions tested

• Caretaker MUAC screening - training by health workers
• Caretaker MUAC screening - training by caregivers

Conditions studied

• Acute Malnutrition in Childhood — all drugs for Acute Malnutrition in Childhood →

Sponsor

University of California, San Francisco

Who can join

Adults 6 Months to 59 Months, any sex, with Acute Malnutrition in Childhood. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This project includes a pilot cluster-randomized trial of the efficacy of training caregivers to screen for acute malnutrition (AM) in children aged 6-59 months using mid-upper arm circumference (MUAC) in Burkina Faso. The pilot will be conducted to establish the feasibility of procedures and preliminary outcome data to inform the sample size calculations and design of a future longer-term, fully powered cluster-randomized trial. Forty communities enrolled in the Bill \& Melinda Gates Foundation-funded Child Health with Azithromycin Treatment (CHAT) trial will be randomly selected for this pilot and randomized to receive the caregiver training intervention or no additional intervention. All communities will continue to receive standard of care screening for AM according to national guidelines, which includes community-based screening for AM by community health workers using MUAC every 6 months. A baseline census will be conducted before randomization to enumerate the eligible population of caregivers and children 6-59 months old and measure MUAC. A final census with MUAC measurement will be conducted 6 months later (primary outcome). Data will be collected on all children presenting to the Centre de Santé et Promotion Sociale (CSPS) for malnutrition to track secondary outcomes.

During intervention training, we will also conduct a diagnostic accuracy study to evaluate the validity of caregiver screening by comparing the MUAC measurements of caregivers against the gold standard measurement of the experienced health personnel conducting the training. Also during training, intervention communities will be randomized to one of two training approaches: training by caregivers or training by health agents and adherence to the protocol during follow-up monitoring visits will be compared to determine effectiveness of training.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.