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NCT07106307
Evaluation of Different Root Canal Obturation Techniques
NA trial testing Bioceramic Sealer in Apical Periodontitis in 168 participants. Completed in 15 May 2025.
15 May 2025
Quick facts
| Lead sponsor | Medipol University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 168 |
| Start date | 1 November 2023 |
| Primary completion | 15 May 2025 |
| Estimated completion | 15 May 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bioceramic Sealer — full drug profile →
- Warm Vertical Compaction
- Epoxy Resin-Based Sealer
- Cold Lateral Compaction
Conditions studied
- Apical Periodontitis — all drugs for Apical Periodontitis →
- Periapical Lesion — all drugs for Periapical Lesion →
Sponsor
Medipol University
Who can join
Adults 18 to 60, any sex, with Apical Periodontitis or Periapical Lesion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this clinical study is to evaluate the effect of root canal filling, which is the last stage of root canal treatment (RCT), on the post-operative pain level on single rooted permanent teeth with wide lesions with apical periodontitis, and the effect on the healing of the periapical tissue and lesion by comparing periapical radyography images, which was taken at the beginning and after one year.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Endodontic treatment outcomes in apical periodontitis cases by the lateral condensation versus warm vertical compaction techniques: a one-year follow-up study.
Tahmaz AU, Ersahan S, Erkan E, Hepsenoglu YE, et al · · 2026 · PMID 42063099 · DOI 10.1186/s12903-026-08425-0
Verify or expand the search:
- PubMed search for NCT07106307
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Apical Periodontitis
Currently open trials in the same condition.
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- NCT07307807 — Evaluation of Postoperative Pain and Lesion Healing in Periapical Lesion-Affected Teeth Obturated With Different Root Ca · NA · active not recruiting
- NCT06843525 — Bite Force Measurements · recruiting
- NCT07048028 — Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial) · NA · recruiting
- NCT07448571 — Evaluation of Revitalization Success Using i-PRF in Non-Surgical Root Canal Retreatment · NA · recruiting
Other Medipol University trials
Trials by the same sponsor.
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- NCT07534488 — Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07106307 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medipol University
- Last refreshed: 6 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07106307.
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