NCT07214636

Development and Investigation of the ApneaTheraPlay

Not yet recruiting NA Last updated 20 January 2026

What this trial tests

NA trial testing Structured Pre-Sleep Exercise in Apnea, Obstructive in 54 participants. Not yet recruiting.

Timeline

2 May 2026

Primary endpoint
1 August 2027

1 December 2027

Quick facts

Lead sponsor	Medipol University
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	54
Start date	2 May 2026
Primary completion	1 August 2027
Estimated completion	1 December 2027
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Structured Pre-Sleep Exercise
• ApneaTheraPlay (ATP)

Conditions studied

• Apnea, Obstructive — all drugs for Apnea, Obstructive →
• Exercise Addiction — all drugs for Exercise Addiction →
• Physiotherapy and Rehabilitation — all drugs for Physiotherapy and Rehabilitation →

Sponsor

Medipol University

Who can join

Adults 18 to 65, any sex, with Apnea, Obstructive or Exercise Addiction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obstructive Sleep Apnea Syndrome (OSAS) is commonly treated with CPAP devices, but adherence rates are low. Exercise has been shown to strengthen respiratory muscles, improve upper airway function, and enhance sleep quality. However, most studies have examined only single or dual exercise protocols, and there is little evidence regarding integrated programs with four exercise types or their effects when performed directly before sleep.

This project aims to develop and evaluate ApneaTheraPlay (ATP), a digital gamified video-based exercise platform combining respiratory, aerobic, strengthening, and oropharyngeal exercises. The randomized controlled, double-blind study will allocate participants into three groups: ATP, a structured pre-sleep exercise group (SPEG), and a control group (CG). Intervention groups will exercise three times per week for 12 weeks, while the control group will only keep a physical activity diary.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Development and investigation of the efficacy of an interactive, web-based game exercise system (ApnoeaTheraPlay) for individuals with obstructive sleep apnoea syndrome: study protocol for a randomised, single-blind, controlled trial.
   Aras Bayram G, Tarakci D, Ergezen Sahin G, Savas Cevlan G, et al · · 2026 · PMID 41951254 · DOI 10.1136/bmjopen-2026-117541