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NCT07090720
Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary Hypertension
NA trial testing Melatonin in Melatonin in 80 participants. Completed in 1 January 2025.
1 January 2025
Quick facts
| Lead sponsor | Tanta University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 1 January 2023 |
| Primary completion | 1 January 2025 |
| Estimated completion | 1 January 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Melatonin (MELATONIN) — full drug profile →
- Placebo
Conditions studied
- Melatonin — all drugs for Melatonin →
- Left Ventricular Function — all drugs for Left Ventricular Function →
- Neonates — all drugs for Neonates →
- Persistent Pulmonary Hypertension — all drugs for Persistent Pulmonary Hypertension →
Sponsor
Tanta University
Who can join
36 Weeks and older, any sex, with Melatonin or Left Ventricular Function. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aimed to evaluate the effect of melatonin on the left ventricular function in neonates with persistent pulmonary hypertension
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Melatonin effects on the left ventricular function in neonates with persistent pulmonary hypertension.
Nofal SM, El-Mashad AM, Elmesiry AM, Abouelenain AM, et al · · 2026 · PMID 41954764 · DOI 10.1007/s00431-026-06864-z
Verify or expand the search:
- PubMed search for NCT07090720
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Melatonin
Trials testing the same drug.
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- NCT07503600 — The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections · Phase 3 · not yet recruiting
- NCT07375342 — Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric · NA · enrolling by invitation
- NCT07305350 — EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATES · Phase 2 · active not recruiting
- NCT07096635 — Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction · NA · not yet recruiting
Other recruiting trials for Melatonin
Currently open trials in the same condition.
- NCT07344467 — Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery · NA · recruiting
- NCT06812026 — Effects of Melatonin and Massage After Third Molar Surgery · active not recruiting
- NCT06687304 — Light in Healthcare Environment (Ljus i sjukhusmiljö) · NA · recruiting
- NCT06502613 — Idiopathic Scoliosis New Onset and Melatonin Phase Delay in Children · recruiting
Other Tanta University trials
Trials by the same sponsor.
- NCT07398651 — Apremilast and Adalimumab in Psoriatic Arthritis Patients · NA · not yet recruiting
- NCT06966856 — This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcti · Phase 3 · not yet recruiting
- NCT07334197 — Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy · NA · not yet recruiting
- NCT07498998 — Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome · NA · not yet recruiting
- NCT07114250 — Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07090720 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tanta University
- Last refreshed: 29 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07090720.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing