Last reviewed · How we verify
Melatol (MELATONIN)
At a glance
| Generic name | MELATONIN |
|---|---|
| Sponsor | Rad Neurim Pharmaceuticals Eec Sarl |
| Drug class | Adrenocorticotropic Hormone [EPC] |
| Target | Melatonin receptor type 1B |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
| First approval | 2007 |
Approved indications
- Disorders of initiating and maintaining sleep
Common side effects
Drug interactions
- nifedipine
Key clinical trials
- Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp. (NA)
- A Study of Melatonin Concentration During Lactation
- Melatonin for Treatment of Delirium in Critically Ill Adult Patients (PHASE2)
- PICU-related Sleep and Circadian Dysregulation Pilot Study (NA)
- Studying Melatonin and Recovery in Teens (NA)
- Effect of Esketamine on Postoperative Sleep in Postmenopausal Women (NA)
- The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries (PHASE4)
- Melatonin Versus Placebo for Bipolar Disorder (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |