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NCT06889870: pain
Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.
NA trial testing Pectoral Nerve Block in Pain in 134 participants. Currently enrolling.
30 March 2026
Quick facts
| Lead sponsor | Faculdade de Ciências Médicas de Minas Gerais |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 134 |
| Start date | 15 April 2025 |
| Primary completion | 30 March 2026 |
| Estimated completion | 30 July 2026 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Pectoral Nerve Block — full drug profile →
- Local Anesthesia — full drug profile →
Conditions studied
- Pain — all drugs for Pain →
- Pain Management — all drugs for Pain Management →
- Anesthesia — all drugs for Anesthesia →
Sponsor
Faculdade de Ciências Médicas de Minas Gerais
Who can join
Adults 18 to 80, female only, with Pain or Pain Management. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors. Breast cancer surgery is an important part of treatment and post-operative pain needs to be adequately prevented and treated. This prospective, randomized, double-blind clinical study aims to evaluate the efficacy of interfascial pectoral nerve block (PECS II) compared to local anesthetic infiltration at the surgical site in patients undergoing breast cancer surgery in terms of pain and nausea. Data collection will be carried out at the Nossa Senhora das Dores Hospital with 133 patients, who will be divided into two groups: the PEC group will undergo PECS II blockade and the LOC group will undergo local anesthetic infiltration at the surgical site. Both interventions will be performed after the induction of opioid-free/sparing balanced general anesthesia. At the end of surgery, the patients will be taken to the post-anesthetic recovery room (PACU), where post-operative pain will be monitored on arrival and at 30-minute intervals up to two hours after surgery, and before the patient is discharged the following day. A visual analog scale (VAS) will be used, and PONVs will also be recorded. After a 2-hour stay in the PACU, they will be transferred to the ward, and after 24 hours, they will be reassessed using the same parameters. Opioid consumption will be recorded in the PACU and during hospitalization, as well as the occurrence of nausea or vomiting and compared between the groups, and side effects and complications will be monitored.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06889870
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Pectoral Nerve Block
Trials testing the same drug.
- NCT06758765 — Erector Spinae Plane Block vs. PECS I-II Blocks After Breast-conserving Surgery · NA · completed
- NCT04086394 — PECS Block in Partial Mastectomy for Postoperative Pain Control · NA · unknown
- NCT03152929 — Paravertebral Block (PVC) Versus Pectoral Nerve Block (PEC) · Phase 3 · terminated
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- NCT07454993 — The Effect of Music During Colonoscopy · NA · recruiting
Other Faculdade de Ciências Médicas de Minas Gerais trials
Trials by the same sponsor.
- NCT07388953 — Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimall · NA · recruiting
- NCT06813352 — Analysis of Facial Expressions for Pain Recognition in Fibromyalgia: Using Artificial Intelligence and Biomarkers · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06889870 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Faculdade de Ciências Médicas de Minas Gerais
- Last refreshed: 16 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06889870.
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