Last reviewed · How we verify
Pain
Approved treatments
- Renacidin · Baxter
Renacidin works by inhibiting the formation of calcium oxalate crystals in the urine, which can help prevent kidney stones. - Xibrom · Bp Consulting, Inc
- Magan
- DEXIBUPROFEN
- Trilisate
Trilisate works by blocking the production of prostaglandins, hormone-like substances that cause pain and inflammation. - Propoxyphene Compound 65
- Nalfon · Pharmaco
- Tussionex Pennkinetic · Teva
Tussionex Pennkinetic works by binding to opioid receptors in the brain, which helps to reduce pain and congestion. - Yellox · University of Trieste
- Dentastat · Energique, Inc.
- Synalgos-Dc · Caraco
- Hemorrhoid, Fissure, ProctalgiaSuppositories · WU XI ZHONG ZHI WEI NA TECHNOLOGY CO., Ltd.
Proctalgia Suppositories works by interacting with the anal tissue to reduce symptoms of irritation, pain, and discomfort. - Ultram · Janssen
- Dilaudid-Hp · Fresenius Kabi
Hydromorphone binds primarily to mu-opioid receptors, producing analgesia without a ceiling effect. - Voltaren · Hisamitsu Pharmaceutical Co., Inc
- Narcan · Adapt
- Norgesic · Hikma
- SIMETRIDE
- Lorcam
Lorcam works by blocking the COX-2 enzyme, which reduces the production of prostaglandins that cause pain and inflammation. - Reufenac
- Fentanyl (F2) · Oslo University Hospital
- Nandron
- pethidine
- Codeine · Generic (multiple manufacturers)
- Traxam
Traxam works by blocking the production of prostaglandins, hormone-like substances that cause pain and inflammation. - Benzidamine
Benzidamine works by activating soluble guanylate cyclase, an enzyme that produces cyclic guanosine monophosphate (cGMP), leading to pain relief. - Fluphenamic Acid
- Tienoridine
Tienoridine works by binding to the adenosine receptor A1, which helps to reduce pain by modulating the activity of neurons. - Flogene
Flogene works by blocking the action of prostaglandin D2, a chemical that transmits pain signals to the brain. - Dalgan · AstraZeneca
- Duragesic · Johnson & Johnson (Janssen Pharmaceutica)
Synthetic opioid 50-100x more potent than morphine that binds mu-opioid receptors, providing potent analgesia and anesthesia. - Levo-Dromoran · Bausch Health
Levorphanol binds primarily to mu-opioid receptors to produce analgesia, with no ceiling effect for pain relief. - Pethidin · Ain Shams University
- Calmatel
- Lithobid · Generic (multiple manufacturers)
- MS Contin · Generic (multiple manufacturers)
The prototypical opioid agonist that binds mu-opioid receptors in the CNS, providing potent analgesia and serving as the reference standard for all opioids. - Advil · Generic (originally Boots Group)
Ibuprofen inhibits prostaglandin synthetase, reducing pain, fever, and inflammation. - Norgesic · Endo
Orphenadrine citrate centrally acts on brain stem to selectively block facilitatory reticular functions. - Lithium Carbonate
- Acetaminophen · Polymedica
Acetaminophen works by blocking pain signals in the brain. - Meperidine Hydrochloride Preservative Free · Pfizer
Meperidine Hydrochloride Preservative Free works by binding to opioid receptors in the brain, altering the perception of and response to pain. - Dolobid
- Dilaudid-Hp · Fresenius Kabi
Full mu-opioid receptor agonist providing analgesia through CNS opioid receptor activation. - Xibrom · Bausch Health
Xibrom works by blocking the production of prostaglandins, which are hormone-like substances that cause pain and inflammation. - Orudis
- Lodine · Pfizer
- Arthrotec · Pfizer
- Duramorph Pf · Pfizer
Duramorph Pf works by binding to opioid receptors in the brain and spinal cord, mimicking the natural pain-relieving chemicals in the body. - Opana Er · Endo
- Propoxyphene Compound 65
Clinical guidelines
- FDA label — 1L
temporarily relieves minor aches and pains
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Pain patent landscape — cliff calendar, originator estates, attackable patents
- Pain treatment landscape brief
- Pain treatment updates RSS
Frequently asked questions about Pain
What drugs treat Pain?
Tracked treatments include Renacidin, Xibrom, Magan, DEXIBUPROFEN, Trilisate, Propoxyphene Compound 65, Nalfon, Tussionex Pennkinetic.
What is the treatment for Pain?
Standard treatment for Pain includes Renacidin, Xibrom, Magan, DEXIBUPROFEN, Trilisate. See the treatment landscape page for first-line, second-line and salvage options.
What are the treatment guidelines for Pain?
FDA label publishes guidelines for Pain. 1 guideline references tracked.
Related
- Treatment landscape: Pain patent cliff · Pain CI report
- Treatment: Renacidin · Baxter
- Treatment: Xibrom · Bp Consulting, Inc
- Treatment: Magan
- Treatment: DEXIBUPROFEN
- Treatment: Trilisate
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing