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NCT06804434
Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
NA trial testing Lidocaine Intravenous Infusion in Pain in 160 participants. Currently enrolling.
1 February 2026
Quick facts
| Lead sponsor | Osoian Cristiana |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | factorial |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 160 |
| Start date | 18 May 2023 |
| Primary completion | 1 February 2026 |
| Estimated completion | 1 February 2026 |
| Sites | 1 location across Romania |
Drugs / interventions tested
- Lidocaine Intravenous Infusion — full drug profile →
- NOL
Conditions studied
- Pain — all drugs for Pain →
- Anesthesia — all drugs for Anesthesia →
- Perioperative Care — all drugs for Perioperative Care →
Sponsor
Osoian Cristiana
Who can join
18 and older, any sex, with Pain or Anesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06804434
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06804434 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Osoian Cristiana
- Last refreshed: 3 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06804434.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing