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NCT06631625
Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.
Phase 1 trial testing Lidocaine Intravenous Infusion in Pelvic Cancer in 45 participants. Completed in 24 September 2024.
24 September 2024
Quick facts
| Lead sponsor | Alexandria University |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 45 |
| Start date | 24 September 2023 |
| Primary completion | 24 September 2024 |
| Estimated completion | 24 September 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Lidocaine Intravenous Infusion — full drug profile →
- Lidocaine and ketamine
- lidocaine and dexmedetomidine infusion — full drug profile →
Conditions studied
- Pelvic Cancer — all drugs for Pelvic Cancer →
- Abdominal Cancer — all drugs for Abdominal Cancer →
- Surgery — all drugs for Surgery →
- Proinflammatory Cytokines — all drugs for Proinflammatory Cytokines →
Sponsor
Alexandria University
Who can join
Adults 40 to 70, any sex, with Pelvic Cancer or Abdominal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators hypothesize that effect of addition of dexmedetomidine or ketamine by IV infusion to lidocaine infusion may be more beneficial than lidocaine infusion alone on proinflammatory cytokines (IL-1, IL-6 and TNFα), and postoperative pain relief and decreased opioid consumption, reduced Length of stay.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06631625
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Pelvic Cancer
Currently open trials in the same condition.
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Other Alexandria University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06631625 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Alexandria University
- Last refreshed: 8 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06631625.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing