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NCT06599970: DI-MOB

Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility

Recruiting now Last updated 19 September 2024
What this trial tests

trial testing No intervention in Dengue in 810 participants. Currently enrolling.

Timeline
1 June 2024
Primary endpoint
31 December 2026
30 June 2027

Quick facts

Lead sponsorInstitute of Tropical Medicine, Belgium
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment810
Start date1 June 2024
Primary completion31 December 2026
Estimated completion30 June 2027
Sites1 location across Cuba

Drugs / interventions tested

Conditions studied

Sponsor

Institute of Tropical Medicine, Belgium

Who can join

Adults 19 to 75, any sex, with Dengue or Arbovirus Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In contrast to the trend expected based on existing prediction models, dengue incidence was historically low during the pandemic mobility restrictions of 2020-2021 in most dengue endemic countries. This highlights that current transmission models do not correctly take human mobility into account. Within a pilot-study in Cienfuegos, South-Central Cuba, we will characterise the epidemiological spread and distribution of dengue outbreaks (2012-2025) in districts repeatedly involved in previous dengue outbreaks as initiating, case-concentrating or transmission sustaining areas. This will be linked with fine-grained mobility data and socio-spatial characterizations of commuting flows and population hubs where people are concentrated during day-time (time when transmission happens). This information, together with entomological and environmental risk-data, will be used to i) improve the accuracy of mathematical dengue models, ii) better understand the transmission process and iii) inform and improve the design of disease control strategies. The project will contribute to much-needed evidence-based guidance for public health actors on improved prevention strategies of epidemics dispersion and where and when to implement control measures.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of No intervention

Trials testing the same drug.

Other recruiting trials for Dengue

Currently open trials in the same condition.

Other Institute of Tropical Medicine, Belgium trials

Trials by the same sponsor.

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Data sources for this page

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