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NCT06894901
Impact of IIT-SIT on Dengue Clusters
NA trial testing Biological (Male Wolbachia-infected Aedes aegypti) in Dengue in 900 participants. Currently enrolling.
20 July 2027
Quick facts
| Lead sponsor | National Environment Agency, Singapore |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 900 |
| Start date | 20 March 2025 |
| Primary completion | 20 July 2027 |
| Estimated completion | 20 January 2028 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- Biological (Male Wolbachia-infected Aedes aegypti) — full drug profile →
Conditions studied
- Dengue — all drugs for Dengue →
Sponsor
National Environment Agency, Singapore
Who can join
Eligibility, any sex, with Dengue. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial aims to evaluate the efficacy of Wolbachia-infected male mosquitoes combined with sterile insect technique (IIT-SIT) to mitigate active dengue transmission in Singapore.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06894901
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Biological (Male Wolbachia-infected Aedes aegypti)
Trials testing the same drug.
- NCT05505682 — Impact of Project Wolbachia - Singapore on Dengue Incidence · NA · completed
Other recruiting trials for Dengue
Currently open trials in the same condition.
- NCT07501793 — Demographic Characteristics of TAK-003 Dengue Vaccine Recipients in Vietnam · active not recruiting
- NCT07358910 — Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective · recruiting
- NCT07007585 — Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection · recruiting
- NCT07158190 — Evaluation of T-cell Responses After Vaccination With the Attenuated Tetravalent Dengue Vaccine (Takeda). · active not recruiting
- NCT06599970 — Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility · recruiting
Other National Environment Agency, Singapore trials
Trials by the same sponsor.
- NCT05505682 — Impact of Project Wolbachia - Singapore on Dengue Incidence · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06894901 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Environment Agency, Singapore
- Last refreshed: 25 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06894901.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing