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NCT06273735
Prospective Trial: Acute Myocardial Injury After Radical Prostatectomy
trial testing Pre- and postoperative determination of troponin as part of the study and 24-month FU survey in Myocardial Injury in 1,000 participants. Completed in 26 August 2025.
28 February 2024
Quick facts
| Lead sponsor | Martini-Klinik am UKE GmbH |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 14 August 2023 |
| Primary completion | 28 February 2024 |
| Estimated completion | 26 August 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Pre- and postoperative determination of troponin as part of the study and 24-month FU survey
Conditions studied
- Myocardial Injury — all drugs for Myocardial Injury →
Sponsor
Martini-Klinik am UKE GmbH — full company profile →
Who can join
18 and older, male only, with Myocardial Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective observational study investigates the incidence of acute myocardial injury after radical prostatectomy for prostate cancer. Consecutive patients undergoing elective open or robot-assisted radical prostatectomy at the Martini-Klinik are included. High-sensitivity cardiac troponin I (hs-cTnI) is measured preoperatively and on postoperative days 1 and 2 to identify acute myocardial injury, defined according to the 4th Universal Definition of Myocardial Infarction. Secondary outcomes include the incidence of myocardial infarction, major adverse cardiac and cerebrovascular events, and mortality during the hospital stay and at 24 months. Baseline patient characteristics (age, BMI, cardiovascular risk factors including the Revised Cardiac Risk Index, comorbidities, and prior cardiac therapy) as well as surgical and tumor-specific parameters are recorded. Associations between acute myocardial injury and clinical variables are analyzed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06273735
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Martini-Klinik am UKE GmbH trials
Trials by the same sponsor.
- NCT04172649 — Acupuncture With Press Tack Needles for Perioperative Pain After Open Radical Prostatectomy · NA · completed
- NCT04324983 — Identification of Predictive Biomarkers · NA · completed
- NCT04271579 — Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s) · NA · recruiting
- NCT06284135 — MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles · NA · completed
- NCT03091231 — Multiparametric Ultrasound-Study for the Detection of Prostate Cancer · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06273735 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Martini-Klinik am UKE GmbH
- Last refreshed: 3 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06273735.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing