Who is sponsoring NCT03091231?

NCT03091231 is sponsored by Martini-Klinik am UKE GmbH.

What drugs are being tested in NCT03091231?

Interventions in NCT03091231: mpUS multiparametric Ultrasound.

What condition does NCT03091231 study?

NCT03091231 studies Prostate Cancer.

Is NCT03091231 still recruiting?

NCT03091231 is currently completed. Last updated 12 April 2023.

Last reviewed 2023-04-12 · How we verify

NCT03091231

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Multiparametric Ultrasound-Study for the Detection of Prostate Cancer

Completed Last updated 12 April 2023

What this trial tests

trial testing mpUS multiparametric Ultrasound in Prostate Cancer in 50 participants. Completed in 31 March 2018.

Timeline

15 May 2017

Primary endpoint
31 December 2017

31 March 2018

Quick facts

Lead sponsor	Martini-Klinik am UKE GmbH
Status	Completed
Study type	OBSERVATIONAL
Enrollment	50
Start date	15 May 2017
Primary completion	31 December 2017
Estimated completion	31 March 2018
Sites	1 location across Germany

Drugs / interventions tested

mpUS multiparametric Ultrasound

Conditions studied

Prostate Cancer — all drugs for Prostate Cancer →

Sponsor

Martini-Klinik am UKE GmbH — full company profile →

Who can join

Adults 18 to 75, male only, with Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of the study is the matching of sensitivity, specificity, the negative predicate value and the positive predictive value of Contrast-Enhanced Ultrasound (CEUS), Shear Wave Elastography (SWE) and the combination to detect clinically significant prostate carcinoma foki. Conventional ultrasound is insufficient to safely display prostate carcinoma. Therefore, other imaging agents are recently added to improve the detection of tumor foci. These include innovative imaging ultrasound methods and multiparametric MRI.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Automated multiparametric localization of prostate cancer based on B-mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics.
Wildeboer RR, Mannaerts CK, van Sloun RJG, Budäus L, et al · · 2020 · cited 77× · PMID 31602512 · DOI 10.1007/s00330-019-06436-w
Multiparametric ultrasound: evaluation of greyscale, shear wave elastography and contrast-enhanced ultrasound for prostate cancer detection and localization in correlation to radical prostatectomy specimens.
Mannaerts CK, Wildeboer RR, Postema AW, Hagemann J, et al · · 2018 · cited 18× · PMID 30409150 · DOI 10.1186/s12894-018-0409-5

Verify or expand the search:

Other recruiting trials for Prostate Cancer

Currently open trials in the same condition.

NCT06960798 — Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno) · recruiting
NCT07237269 — Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer · Phase 2 · recruiting
NCT07234981 — PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer · Phase 2 · recruiting
NCT07027124 — Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Ris · Phase 2 · recruiting
NCT07426094 — PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate · Phase 2, PHASE3 · recruiting

Other Martini-Klinik am UKE GmbH trials

Trials by the same sponsor.

NCT06273735 — Prospective Trial: Acute Myocardial Injury After Radical Prostatectomy · completed
NCT04172649 — Acupuncture With Press Tack Needles for Perioperative Pain After Open Radical Prostatectomy · NA · completed
NCT04324983 — Identification of Predictive Biomarkers · NA · completed
NCT04271579 — Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s) · NA · recruiting
NCT06284135 — MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03091231 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Martini-Klinik am UKE GmbH
Last refreshed: 12 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03091231.

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