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NCT06230497
Correlation Analysis Between Mostcare Parameters and Spontaneous Breathing Trial in Patients After Cardiac Surgery
trial in Post-cardiac Surgery in 50 participants. Completed in 10 October 2024.
1 October 2024
Quick facts
| Lead sponsor | Peking Union Medical College Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 May 2024 |
| Primary completion | 1 October 2024 |
| Estimated completion | 10 October 2024 |
| Sites | 1 location across China |
Conditions studied
- Post-cardiac Surgery — all drugs for Post-cardiac Surgery →
- Ventilator Weaning — all drugs for Ventilator Weaning →
Sponsor
Peking Union Medical College Hospital
Who can join
Adults 18 to 80, any sex, with Post-cardiac Surgery or Ventilator Weaning. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cardiac output (CO) monitoring is of primary importance in high-risk surgery and critically ill patients. Intermittent thermodilution (ThD) by means of a pulmonary artery catheter (PAC) was invasiveness, the occurrence of complications, and inability to estimate CO on a beat-by-beat basis may explain the reduction in routine use. Echocardiography is now widely used. However, a poor acoustic window, inaccurate diameter calculations, and difficulty maintaining the angle of insonation and blood flow within the recommended values may lead to inaccuracy in CO estimation.Pulse contour methods (PCMs) are commonly used as they seem to fulfill most of the characteristics of an "ideal" hemodynamic monitoring system. Mostcare can continuously and real-time monitor important circulatory indicators such as cardiac output, peripheral vascular resistance index (SVRI), cardiovascular impedance (Ztot), cardiac cycle efficiency (CCE), and maximum pressure gradient (dp/dt MAX). It may help identify the causes of difficulty in weaning patients from ventilators after cardiac surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Pressure record analysis method parameters during weaning success and failure from mechanical ventilation in prolonged ventilated patients after cardiac surgery.
Zhou Y, Liu S, Mi L, Yang Y, et al · · 2025 · PMID 41376952 · DOI 10.21037/jtd-2025-1194
Verify or expand the search:
- PubMed search for NCT06230497
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
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Currently open trials in the same condition.
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Other Peking Union Medical College Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06230497 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking Union Medical College Hospital
- Last refreshed: 14 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06230497.
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