NCT06613178 (IVACS) is a Phase 4 clinical trial of acetaminophen in Post Operative Delirium, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.

What drugs are being tested in NCT06613178?

Interventions in NCT06613178: acetaminophen.

What condition does NCT06613178 study?

NCT06613178 studies Post Operative Delirium, Post Operative Pain, Post-Op Complication, Post-cardiac Surgery.

Is NCT06613178 still recruiting?

NCT06613178 is currently recruiting now. Last updated 25 September 2024.

Last reviewed 2024-09-25 · How we verify

NCT06613178: IVACS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intravenous Acetaminophen After Cardiac Surgery - Definitive Study

Recruiting now Phase 4 Last updated 25 September 2024

What this trial tests

Phase 4 trial testing acetaminophen in Post Operative Delirium in 1,100 participants. Currently enrolling.

Timeline

2 July 2024

Primary endpoint
1 July 2027

15 December 2027

Quick facts

Lead sponsor	McGill University Health Centre/Research Institute of the McGill University Health Centre
Phase	Phase 4
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	1,100
Start date	2 July 2024
Primary completion	1 July 2027
Estimated completion	15 December 2027
Sites	8 locations across Canada

Drugs / interventions tested

acetaminophen (Paracetamol) — full drug profile →

Conditions studied

Post Operative Delirium — all drugs for Post Operative Delirium →
Post Operative Pain — all drugs for Post Operative Pain →
Post-Op Complication — all drugs for Post-Op Complication →
Post-cardiac Surgery — all drugs for Post-cardiac Surgery →

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Who can join

18 and older, any sex, with Post Operative Delirium or Post Operative Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Double blind, double dummy trial of the use of IV acetaminophen versus oral acetaminophen for the prevention of delirium after cardiac surgery. The underlying hypothesis is that better pain control and less use of narcotics will lead to a lower incidence of delirium from day 1 to 7 following cardiac surgery. Other important secondary outcomes are the total use of narcotics, ICU and hospital stay, improved cognitive function at 6 months and 1 year post surgery, NSAID use at each centre and associated NSAID complications.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of acetaminophen

Trials testing the same drug.

NCT05246644 — IV Acetaminophen After Cardiac Surgery - PILOT · Phase 3 · unknown
NCT04918147 — Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD) · Phase 2 · terminated
NCT04662567 — Oral Versus Intravenous Acetaminophen for Postoperative Pain Control · NA · terminated
NCT04165096 — KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in P · Phase 2 · completed
NCT03994731 — Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout · Phase 4 · completed

Other McGill University Health Centre/Research Institute of the McGill University Health Centre trials

Trials by the same sponsor.

NCT07439406 — Comparing Standard and Autoclaved Peanut Oral Immunotherapy in People With Peanut Allergy · Phase 2 · not yet recruiting
NCT07328971 — Vancomycin Taper to Prevent Recurrent Clostridioides Difficile · Phase 3 · not yet recruiting
NCT07556952 — Dex & Mastectomy Pain · Phase 4 · recruiting
NCT07069582 — Pharmacokinetics of Antituberculosis Drugs in Breastfeeding Women · Phase 1 · not yet recruiting
NCT07386171 — Micro-Ultrasound for Detecting Clinically Significant Prostate Cancer in Active Surveillance · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06613178 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by McGill University Health Centre/Research Institute of the McGill University Health Centre
Last refreshed: 25 September 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06613178.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing