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NCT06220825: PRoVent-PED
PRactice of VENTilation in Critically Ill PEDiatric Patients
trial in Critical Illness in 2,500 participants. Currently enrolling.
1 April 2034
Quick facts
| Lead sponsor | University Medical Center Groningen |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,500 |
| Start date | 1 April 2024 |
| Primary completion | 1 April 2034 |
| Estimated completion | 1 April 2034 |
| Sites | 1 location across Netherlands |
Conditions studied
- Critical Illness — all drugs for Critical Illness →
- Respiratory Failure — all drugs for Respiratory Failure →
Sponsor
University Medical Center Groningen
Who can join
Under 18, any sex, with Critical Illness or Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this worldwide observational study is to investigate ventilation practice in critically ill pediatric patients. The main questions it aims to answer are: 1. What is the global current practice of ventilatory support in critically ill pediatric patients? 2. Which potentially modifiable factors related to ventilation are associated with outcome? Participating pediatric intensive care units will gather detailed information about ventilation practice and outcome, such as duration of ventilatory support, length of ICU stay and ICU mortality.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Practice of ventilation in critically ill pediatric patients: protocol for an international, long-term, observational study, and results of the pilot feasibility study.
van Vliet R, Melger JWJ, Paulus F, Bem RA, et al · · 2025 · cited 2× · PMID 40435034 · DOI 10.62675/2965-2774.20250398 -
Epidemiology, ventilation management, and clinical outcomes in children (PRoVENT-PED): first results from the 10-year, investigator-initiated, international, multicentre, prospective cohort study.
van Vliet R, Melger JWJ, Bem RA, Blokpoel RGT, et al · · 2026 · PMID 42081907 · DOI 10.1016/s2213-2600(26)00044-5 -
The PROtective VEntilation (PROVE) Network - advancing research and collaboration in mechanical ventilation.
Schultz MJ, Ball L, Bernardi M, Battaglini D, et al · · 2025 · PMID 40929471 · DOI 10.62675/2965-2774.20250399
Verify or expand the search:
- PubMed search for NCT06220825
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University Medical Center Groningen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06220825 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Center Groningen
- Last refreshed: 7 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06220825.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing