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NCT07439237
Implant-supported Maxillary Overdentures; a 15-years Evaluation
trial testing Maxillary overdenture supported by dental implants in Edentulous Maxilla, Atrophic in 116 participants. Not yet recruiting.
1 November 2026
Quick facts
| Lead sponsor | University Medical Center Groningen |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 116 |
| Start date | 1 May 2026 |
| Primary completion | 1 November 2026 |
| Estimated completion | 1 November 2026 |
Drugs / interventions tested
- Maxillary overdenture supported by dental implants
Conditions studied
- Edentulous Maxilla, Atrophic — all drugs for Edentulous Maxilla, Atrophic →
- Implants, Dental — all drugs for Implants, Dental →
- Overdenture — all drugs for Overdenture →
Sponsor
University Medical Center Groningen
Who can join
18 and older, any sex, with Edentulous Maxilla, Atrophic or Implants, Dental. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
* Background Patients experiencing problems with their conventional maxillary denture can benefit from implant- retained overdentures. Bar-retained implant overdentures can be supported by 4 or 6 implants, splinted by a bar. Evidence on maxillary implant overdentures has been mostly short to medium term, non-comparing or retrospective. Even more, 15-years data of comparative studies are lacking. It is important to evaluate treatment outcomes, such as implant survival, peri-implant bone changes and patient satisfaction at the long-term. * Main research question The aim of this 15-years study is to evaluate a patient group treated 15 years ago in a prospective study with a maxillary overdenture on 4 or 6 implants in an edentulous maxilla. The primary objective of the study is to analyze marginal bone level changes by radiological assessments at 15-years follow-up. Secondary objectives are implant and overdenture survival, condition of peri- implant mucosa and patients' satisfaction. * Design (including population, confounders/outcomes) The study design is an observational study of a group of patients which were treated 15 years ago with dental implants and an overdenture in the maxilla because of problems with retention and stability with their conventional denture. Outcomes: primary outcome is the change in marginal peri-implant bone level 15 years after placing the overdenture. Secondary outcome measures will be implant and overdenture survival, peri-implant mucosa health and patients' satisfaction using a questionnaire. * Expected results Stable peri-implant bone levels, high implant and overdenture survival rate and satisfied patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07439237 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Center Groningen
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07439237.
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