Last reviewed · How we verify
NCT06197503: PHYSTAVIII
Randomized Study of Physiological vs Right Ventricular Pacing in Patients With Normal Ventricular Function Post TAVI
NA trial testing Conduction system pacing in Transcatheter Aortic Valve Implantation in 48 participants. Currently enrolling.
15 December 2025
Quick facts
| Lead sponsor | Hospital Clinic of Barcelona |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 30 November 2023 |
| Primary completion | 15 December 2025 |
| Estimated completion | 15 December 2026 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Conduction system pacing
- Right ventricular pacing
Conditions studied
- Transcatheter Aortic Valve Implantation — all drugs for Transcatheter Aortic Valve Implantation →
- Physiological Pacing — all drugs for Physiological Pacing →
- Right Ventricular Pacing — all drugs for Right Ventricular Pacing →
- AV Block — all drugs for AV Block →
Sponsor
Hospital Clinic of Barcelona
Who can join
18 and older, any sex, with Transcatheter Aortic Valve Implantation or Physiological Pacing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Single-center randomized trial in patients with pacing indication (AV block) after TAVI (transfemoral aortic valve implantation) and LVEF\> 50%, that aims to study the percentage of patients who improve at 12 months in a combined clinical endpoint.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06197503
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Conduction system pacing
Trials testing the same drug.
- NCT07276490 — Central Haemodynamics and Pacing for AV Block · NA · recruiting
- NCT07430553 — Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure · NA · recruiting
- NCT06241651 — CSP Versus BiVP for Heart Failure Patients with RVP Upgraded to Cardiac Resynchronization Therapy · NA · recruiting
- NCT06088927 — Long-term Outcomes of Conduction System Pacing: a National Multicenter Observational Study - NORMAND'HIS / STIMU'HIS · recruiting
- NCT05572736 — Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart Failure · NA · completed
Other recruiting trials for Transcatheter Aortic Valve Implantation
Currently open trials in the same condition.
- NCT06773780 — Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block a · NA · recruiting
- NCT06602609 — Remote Cardiovascular Monitoring in Post-TAVI Patients · NA · recruiting
- NCT06896227 — TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics · NA · recruiting
- NCT06481137 — Reversibility of Cardiac Conduction Disturbances Following TAVI · NA · recruiting
- NCT06189976 — Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation · NA · recruiting
Other Hospital Clinic of Barcelona trials
Trials by the same sponsor.
- NCT07509814 — Extended Versus Short Prehabilitation Programme for Patients With Advanced Ovarian Cancer Undergoing Major Surgery · NA · not yet recruiting
- NCT07469358 — iCBT for Adolescents Obsessive-compulsive Dissorder · NA · active not recruiting
- NCT07358611 — Non-invasive Mapping-Guided Atrial Fibrillation Ablation · NA · recruiting
- NCT07237867 — Frequency-Dependent Effects of Percutaneous Femoral Nerve Stimulation on Quadriceps Strength in Athletes With Patellar T · NA · recruiting
- NCT07163936 — Analysis of the Influence of Dialysis Fluid Composition on Vascular Calcification in Patients With Chronic Kidney Diseas · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06197503 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Clinic of Barcelona
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06197503.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing