Last reviewed · How we verify
NCT06050616: ESTRA-BED
Multimodal Longitudinal and Predictive Modelling to Understand Eating Disorder Development
trial testing MRI scans in Binge-Eating Disorder in 23 participants. Completed in 12 August 2024.
12 August 2024
Quick facts
| Lead sponsor | King's College London |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 23 |
| Start date | 15 November 2023 |
| Primary completion | 12 August 2024 |
| Estimated completion | 12 August 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- MRI scans
- Psychological measures
- Life experiences
- Blood and urine samples — full drug profile →
- Mental health symptoms
Conditions studied
- Binge-Eating Disorder — all drugs for Binge-Eating Disorder →
- Anorexia Nervosa — all drugs for Anorexia Nervosa →
- Bulimia Nervosa — all drugs for Bulimia Nervosa →
Sponsor
King's College London
Who can join
Adults 18 to 30, any sex, with Binge-Eating Disorder or Anorexia Nervosa. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this observational study is to elucidate the biopsychosocial (including neural, psychological, and social) basis of eating disorders (EDs). The investigators will use functional and structural neuroimaging, psychological as well as environmental data to identify both shared and distinct behavioural/neural processes across ED diagnoses. The investigators will use advanced statistical methods such as machine learning based models. The investigators will carry out analysis on the data already collected in the STRATIFY (Brain network based stratification of reinforcement-related disorders, IRAS ID 218030) and IMAGEN studies (Reinforcement-related behaviour in normal brain function and psychopathology, reference PNM/10/11-126), including participants with Anorexia Nervosa (N=60), Bulimia Nervosa (N=52), Binge eating disorder (N=27) and healthy controls. In addition, the investigators will recruit 30 new participants with a binge eating disorder using the original STRATIFY study protocol to enlarge the binge eating disorder group, so that its sample size is comparable to the other groups. Participants will complete online questionnaires, take an online clinical interview, and undergo a research visit, including brain scans, collection of blood and urine samples, and assessment using a range of cognitive and behavioural measures.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06050616
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of MRI scans
Trials testing the same drug.
- NCT05029258 — Biomarkers for Clinical Hypoxia Evaluation in Cervical Cancer · recruiting
- NCT04594291 — MRI Changes of Acute Kidney Injury in COVID-19 · completed
- NCT04569604 — QoL and Cognitive Function in Patients With Hypoparathyroidism · completed
- NCT03566550 — Gut Imaging for Function & Transit in Cystic Fibrosis Study 1 · completed
Other recruiting trials for Binge-Eating Disorder
Currently open trials in the same condition.
- NCT07060534 — Building Healthy Eating and Self-Esteem Together for University Students · NA · recruiting
- NCT07237607 — Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders · NA · recruiting
- NCT06864065 — Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder · NA · recruiting
- NCT06819813 — Project VIBE: Virtual Intervention for Binge Eating in Adolescents · NA · recruiting
- NCT06485687 — Low Intensity Focused Ultrasound for Binge Eating Disorder · NA · active not recruiting
Other King's College London trials
Trials by the same sponsor.
- NCT07357064 — Professional Decision Making in Childbirth. · not yet recruiting
- NCT07341087 — Skin Inflammation in Perimenopause: A Probiotic Intervention Proof of Concept Trial · NA · recruiting
- NCT07228962 — Cutaneous Biomarkers in Atopic Eczema Using a Non-Invasive Micro-Suction Device in Babies · not yet recruiting
- NCT07365722 — Comparison of Two Non-surgical Procedure to Manage Gum Disease Around Implants. · NA · not yet recruiting
- NCT07378488 — Dance/Movement Therapy for Functional Neurological Disorder · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06050616 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King's College London
- Last refreshed: 11 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06050616.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing